Tumores de Pancreas e periampulares Flashcards

1
Q

Tipo histologico mais F

A

Adenocarcinoma

- Subtipo: ductal

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2
Q

Epidemiologia

A
  • Mais F em homens, negros, > 45 anos
  • AF
  • TTBG
  • OH
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3
Q

Clinica

A
  • As/s
  • Ictericia
  • Dor abdominal
  • Perda ponderal patologica (>10% em 6m ou 5% em 1m)
  • Acolia e Coluria
  • SINAL DE COUVOISIER- TERRIER
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4
Q

SINAL DE COUVOISIER- TERRIER

A

Vesicula palpavel sobredistendida em HD, indolor

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5
Q

DX- IMG

A
  • ELEIÇAO: TC de Abdomen com contraste
  • +S : Ecoendoscopia
  • Coledoco: RNM
  • Duodeno e Papila: Endoscopia
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6
Q

DX - Labs

A
  • CA19.9: Prognostico e acompanhamento
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7
Q

Estadiamento

A

TC de Tx, Abd e pelve

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8
Q

Cenarios

A
  1. Favoravel
    - Tumor
    - Resto ok
  2. Borderline
    - Contato lateral vascular sem invadir
    - Perigozinhooooo
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9
Q

Cenario incuravel

A
  1. Incurável
    - INVASÃO VASCULAR: A. mesenterica sup, tronco celiaco, V. porta, v mesenterica sup.
    - Mtts: figado, pulmao, linfonodos, peritonio
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10
Q

Mtts a peritonio

A
  • Nodulos
  • Espessamento
  • Espessamento do omento
    = Carcinomatose peritoneal
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11
Q

EF da doença incuravel

A
  1. Linfonodos distantes
    - Lindonodo de Irish: Axilar esquerdo
    - Linfonodo de Virchow: supraclavicular esquerdo
  2. Carcinomatose
    - Nodulo de Sister Mary-Joseph
    - Prateleira de Blummer: linfonodomegalias perirretais perceptíveis ao toque retal
    - Ascite
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12
Q

Manejo

A
  1. Suspeita
  2. Exame Dx
  3. Estadiamento
  4. Tto
    - Favoravel: Cx
    - Borderline: cx + NEOadjuvancia
    - Incuravel: Paliativo
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13
Q

Tto favoravel

A

Cx de Whipple

  • Gastroduodenopancretectomia
  • Mto agressiva
  • Mtas complicaçoes
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14
Q

Tto Borderline

A
  • Gastroduodenopancretectomia + resecçao vascular
  • Maior risco
  • Neoadjuvancia: Antes de cx
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15
Q

Tto Incuravel

A
  1. QT paliativa
  2. Via alimentar:
    - Dieta VO ou
    - SNE ou
    - Jejunostomia ou
    - gastroenteroanastomose
  3. Vía biliar:
    CPRE - Papilotomia + protese biliar OU
    -Drenagem transpaerietohepatica da vía ou
    - Derivaçao biliodigestiva
  4. Analgesia
    - Invasao do plexo celiaco
    - Medicamentos ou
    - Ablaçao
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