Tetanus Flashcards

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1
Q

What are the causative organisms for Tetanus?

A

Clostridium tetani

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2
Q

What form of tetanus is Clostridium tetani?

A

Bacterial, gram-positive

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3
Q

What are the most common modes of transmission for Clostridium tetani?

A

Parenteral, direct contact

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4
Q

What are the virulence factors for Clostridium tetani?

A

Tetanospasm exotoxin

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5
Q

How do you culture/diagnose Clostridium tetani infection?

A

Symptomatic

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6
Q

How do you prevent Clostridium tetani infection?

A

Tetanus toxoid immunization

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7
Q

How do you treat Clostridium tetani infection?

A

Combination of passive antitoxin and tetanus toxoid active immunization, metronidazole, muscle relaxants; sedation

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8
Q

What are the epidemiological features of Clostridium tetani?

A

Worldwide, +/- 35,000 newborn deaths annually in developing countries

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