Meningitis Flashcards
What form of meningitis is Neisseria meningitidis?
Bacteria, gram-negative diplococci
What is the most common modes of transmission for Neisseria meningitidis?
Droplet contact
What is the virulence factors for Neisseria meningitidis?
Capsule, endotoxin, IgA protease
How is Neisseria meningitidis culture and diagnosed?
Gram stain/culture of CSF, blood, rapid antigenic tests, oxidase test, PCR
How can you prevent being infected by Neisseria meningitidis?
Conjugated vaccine;
ciprofloxacin. rifampin, ceftriaxone used to protect contacts
What is the treatment method for Neisseria meningitidis?
Ceftriaxone
penicillinn
What is the distinctive features of Neisseria meningitids?
Petechiae
Meningococcemia
Rapid decline
What are the epidemiological features of Neisseria meningitidis?
United States: 14% of bacterial meningitis;
Meningitis belt: 1,000 cases per 100,000 annually
What form of meningitis is Streptococcus pneumoniae?
Bacteria, gram-positive
What are the most common modes of transmission for Streptococcus pneumoniae?
Droplet contact
What are the virulence factors of Streptococcus pneumoniae?
Capsule, induction of apoptosis, hemolysin and hydrogen peroxide production
How is Streptococcus pneumoniae culture/diagnosed?
Gram stain/culture of CSF
How do you prevent infection from Streptococcus pneumoniae?
Two vaccines:
Prevnar (children and adults)
Pneumovax (adults)
How do you treat Streptococcus pneumoniae?
Vancomycin + ceftriaxone or cefotaxime;
resistant S. pneumoniae is categorized by the CDC as a Serious Threat
What are the distinctive factors of Streptococcus pneumoniae?
Serious, acute, most common meningitis in adults
without Petchiae
What are the epidemiological features of Streptococcus pneumoniae?
Most common cause of bacterial meningitis in United States (58% of cases)
What form of meningitis is Haemophilus influenzae?
Bacterial, gram-negative coccobacillus
What are the most common modes of transmission for Haemophilus influenzae?
Droplet contact
What are the virulence factors of Haemophilus influenzae?
Capsule
How is Haemophilus influenzae cultured/diagnosed?
Culture on a chocolate agar
How do you prevent being infected by Haemophilus influenzae?
Hib vaccine, cirprofloxacin, rifampin, or ceftriaxone
How do you treat Haemophilus influenzae infection?
Ceftriaxone