Pharyngitis Flashcards

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1
Q

What are the causative organisms of Pharyngitis?

A

Streptococcus pyogenes, Fusobacterium necrophorum, and Viruses

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2
Q

What form of Pharyngitis is Streptococcus pyogenes?

A

Bacterial, gram-positive

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3
Q

What are the most common modes of transmission for Pharyngitis (Streptococcus pyogenes)?

A

Droplet or direct contact

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4
Q

What are the virulence factors for Pharyngitis (Streptococcus pyogenes)?

A

LTA, M protein, hyaluronic acid capsule, SLS and SLO, superantigens, induction of autoimmunity.

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5
Q

How do you culture/diagnose Pharyngitis (Streptococcus pyogenes)?

A

Beta-hemolytic on blood agar, sensitive to bacitracin, rapid antigen tests

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6
Q

How do you prevent Pharyngitis (Streptococcus pyogenes)?

A

Hygiene practices

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7
Q

How do you treat Pharyngitis (Streptococcus pyogenes)?

A

Penicillin, cephalexin in penicillin-allergic

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8
Q

What are the distinctive features of Pharyngitis (Streptococcus pyogenes)?

A

Generally more severe than viral pharyngitis

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9
Q

What are the epidemiological features of Pharyngitis (Streptococcus pyogenes)?

A

United States: 10% to 20% of all cases of pharyngitis

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10
Q

What form of Pharyngitis is Fusobacterium necrophourum?

A

Bacterial, gram-negative

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11
Q

What are the most common modes of transmission of Pharyngitis (Fusobacterium necrophorum)?

A

Usually endogenous

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12
Q

What are the virulence factors for Pharyngitis (Fusobacterium necrophorum)?

A

Invasiveness, endotoxin

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13
Q

How do you culture/diagnose Pharyngitis (Fusobacterium necrophorum)?

A

Culture anaerobically; CT scan for abscess(es)

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14
Q

How do you prevent Pharyngitis (Fusobacterium necrophorum)?

A

??

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15
Q

How do you treat Pharyngitis (Fusobacterium necrophorum)?

A

Penicillin

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16
Q

What are the distinctive features of Pharyngitis (Fusobacterium necrophorum)?

A

Can lead to Lemierre’s syndrome

17
Q

What are the epidemiological features of Pharyngitis (Fusobacterium necrophorum)?

A

Causes up to 15% of acute pharyngitis in teens/young adults

18
Q

What form of Pharyngitis is Viruses?

A

Virsues

19
Q

What are the most common modes of transmission for Pharyngitis (Viruses)?

A

All forms of contact

20
Q

What are the virulence factors for Pharyngitis (Viruses)?

A
21
Q

How do you culture/diagnose Pharyngitis (Viruses)?

A

Goal is to rule out S. pyogenes (and F. necrophorum); further diagnosis usually not performed

22
Q

How do you treat Pharyngitis (Viruses)?

A

Hygiene practices

23
Q

What are the distinctive features of Pharyngitis (Viruses)?

A

Hoarseness frequently accompanies viral pharyngitis

24
Q

What are the epidemiological features for Pharyngitis (Viruses)?

A

Ubiquitous; responsible for 40% to 60% of all pharyngitis