Pharyngitis Flashcards
What are the causative organisms of Pharyngitis?
Streptococcus pyogenes, Fusobacterium necrophorum, and Viruses
What form of Pharyngitis is Streptococcus pyogenes?
Bacterial, gram-positive
What are the most common modes of transmission for Pharyngitis (Streptococcus pyogenes)?
Droplet or direct contact
What are the virulence factors for Pharyngitis (Streptococcus pyogenes)?
LTA, M protein, hyaluronic acid capsule, SLS and SLO, superantigens, induction of autoimmunity.
How do you culture/diagnose Pharyngitis (Streptococcus pyogenes)?
Beta-hemolytic on blood agar, sensitive to bacitracin, rapid antigen tests
How do you prevent Pharyngitis (Streptococcus pyogenes)?
Hygiene practices
How do you treat Pharyngitis (Streptococcus pyogenes)?
Penicillin, cephalexin in penicillin-allergic
What are the distinctive features of Pharyngitis (Streptococcus pyogenes)?
Generally more severe than viral pharyngitis
What are the epidemiological features of Pharyngitis (Streptococcus pyogenes)?
United States: 10% to 20% of all cases of pharyngitis
What form of Pharyngitis is Fusobacterium necrophourum?
Bacterial, gram-negative
What are the most common modes of transmission of Pharyngitis (Fusobacterium necrophorum)?
Usually endogenous
What are the virulence factors for Pharyngitis (Fusobacterium necrophorum)?
Invasiveness, endotoxin
How do you culture/diagnose Pharyngitis (Fusobacterium necrophorum)?
Culture anaerobically; CT scan for abscess(es)
How do you prevent Pharyngitis (Fusobacterium necrophorum)?
??
How do you treat Pharyngitis (Fusobacterium necrophorum)?
Penicillin
What are the distinctive features of Pharyngitis (Fusobacterium necrophorum)?
Can lead to Lemierre’s syndrome
What are the epidemiological features of Pharyngitis (Fusobacterium necrophorum)?
Causes up to 15% of acute pharyngitis in teens/young adults
What form of Pharyngitis is Viruses?
Virsues
What are the most common modes of transmission for Pharyngitis (Viruses)?
All forms of contact
What are the virulence factors for Pharyngitis (Viruses)?
How do you culture/diagnose Pharyngitis (Viruses)?
Goal is to rule out S. pyogenes (and F. necrophorum); further diagnosis usually not performed
How do you treat Pharyngitis (Viruses)?
Hygiene practices
What are the distinctive features of Pharyngitis (Viruses)?
Hoarseness frequently accompanies viral pharyngitis
What are the epidemiological features for Pharyngitis (Viruses)?
Ubiquitous; responsible for 40% to 60% of all pharyngitis