Chagas Disease Flashcards
What is the causative organism for Chagas Disease?
Trypanosoma cruzi (Prion)
What are the most common modes of transmission for Chagas Disease (Trypanosoma cruzi)?
Biological vector (triatomine bug), vertical
What are the virulence factors for Chagas Disease (Trypansoma cruzi)?
Antioxidant enzymes, co-opting host antigens; induces autoimmunity
How do you culture/diagnose Chagas Disease (Trypanosoma cruzi)?
Blood smear in acute phase; serological methods in later stages
How do you prevent Chagas Disease (Trypanosoma cruzi)?
Insect control
How do you treat Chagas Disease (Trypanosoma cruzi)?
Consult CDC
What are the epidemiological features of Chagas Disease (Trypansoma cruzi)?
Endemic in Central and South America; 300,000 cases present in United States; considered a neglected parasitic infection (NPI) (see Insight 22.2)