Hepatitis Flashcards

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1
Q

What are the causative organisms for Hepatitis?

A

Hepatitis A or E virus, Hepatitis B virus, Hepatitis C virus

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2
Q

What form of Hepatitis is Hepatitis A or E virus?

A

Virus

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3
Q

What are the most common modes of transmission for Hepatitis (Hepatitis A or E virus)?

A

Fecal-oral, vehicle

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4
Q

What are the virulence factors for Hepatitis (Hepatitis A or E virus)?

A

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5
Q

How do you culture/diagnose Hepatitis (Hepatitis A or E virus)?

A

IgM serology

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6
Q

How do you prevent Hepatitis (Hepatitis A or E virus)?

A

Hepatitis A vaccine or combined HAV/HBV vaccine

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7
Q

How do you treat Hepatitis (Hepatitis A or E virus)?

A

HAV: hepatitis A vaccine or immune globulin
HEV: immune globulin

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8
Q

What is the incubation period for Hepatitis (Hepatitis A or E virus)?

A

2 to 4 weeks

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9
Q

What are the epidemiological features of Hepatitis (Hepatitis A or E virus)?

A

Hepatitis A, United States: 20,000 cases annually and 40% of adults show evidence of prior infection:; internationally: 1.4 million cases per year; hepatitis E, internationally: 20 million infections per year; 60% in East and South East Asia

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10
Q

What form of Hepatitis is the Hepatitis B virus?

A

Virus

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11
Q

What are the most common modes of transmission for Hepatitis (Hepatitis B virus)?

A

Parenteral (blood contact), direct contact (especially sexual), vertical

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12
Q

What are the virulence factors for Hepatitis (Hepatitis B virus)?

A

Latency

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13
Q

How do you culture/diagnose Hepatitis (Hepatitis B virus)?

A

ELISA

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14
Q

How do you prevent Hepatitis (Hepatitis B virus)?

A

HBV recombinant vaccine

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15
Q

How do you treat Hepatitis (Hepatitis B virus)?

A

Interferon, tenofovir, or entecavir

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16
Q

What is the incubation period for Hepatitis (Hepatitis B virus)?

A

1 to 6 months

17
Q

What are the epidemiological features of Hepatitis (Hepatitis B virus)?

A

Unites States: 19,000 new cases per year; 800,000 to 2.2 million have chronic infection; internationally: 240 million

18
Q

What form of Hepatitis is the Hepatitis C virus?

A

Virus

19
Q

What are the most common modes of transmission for Hepatitis (Hepatitis C virus)?

A

Parenteral (blood contact), vertical

20
Q

What are the virulence factors for Hepatitis (Hepatitis C virus)?

A

Core proteins suppresses immune function?

21
Q

How do you culture/diagnose Hepatitis (Hepatitis C virus)?

A

Serology, also PCR

22
Q

How do you prevent Hepatitis (Hepatitis C virus)?

A
23
Q

How do you treat Hepatitis (Hepatitis C virus)?

A

Sofosbuvir + simperevir

24
Q

What is the incubation period for Hepatitis (Hepatitis C virus)?

A

2 to 8 weeks

25
Q

What are the epidemiological features of Hepatitis (Hepatitis C virus)?

A

United States: estimated 30,000 new diagnoses per year; internationally: 150 million chronically infected