TERMS II Flashcards
• Anemia • Growth retardation • Defective keratinization and pigmentation of hair • Hypothermia • Degenerative changes in aortic elastin • Osteopenia • Mental deterioration
copper deficiency
- Nausea
- Vomiting
- Diarrhea
- Hepatic failure
- Tremor
- Mental deterioration
- Hemolytic anemia
- Renal failure
copper toxicity
menkes disease due to?
low copper
Wilson disease due to?
tx?
elevated copper
penicillamine
- Growth retardation
- ↓ taste and smell
- Alopecia
- Dermatitis
- Diarrhea
- Immune dysfunction
- Failure to thrive
- Gonadal atrophy
- Congenital malformations
- Poor wound healing
zinc deficiency
- Reduced copper absorption
- Gastritis
- Sweating
- Fever
- Nausea
- Vomiting
zinc toxicity
- Impaired glucose tolerance
- Weight loss
- Confusion
- Impaired coordination
chromium deficiency
Occupational:
• Renal failure
• Dermatitis
• Pulmonary cancer
chromium toxicity
Risk Factors for Deficiency of this mineral
- Malnutrition
- Long-term TPN without this mineral
- Short bowel syndrome
- Burns
- Traumatic injuries
chromium
• Cardiomyopathy (Keshan disease) • Heart failure • Muscle degeneration • Mood disorders • Impaired immune function • Male infertility • Exacerbate iodine deficiency
selenium toxicity
- Alopecia
- Nausea
- Vomiting
- Abnormal nails
- Emotional lability
- Peripheral neuropathy
- Garlic odor to breath
- Dermatitis
selenium deficiency
Risk Factors for Deficiency and toxicity of this mineral?
- Chronic TPN without selenium
- Low intake
Risk Factors for Toxicity of this mineral?
• Excess dietary intake
selenium
• Impaired growth and skeletal development • Infertility • Abnormal fat and carbohydrate metabolism • Ataxia • Low fertility
manganese deficiency
- Neurotoxicity
- Parkinson-like symptoms
Occupational • Encephalitis-like syndrome • Parkinson-like syndrome • Psychosis • Pneumoconiosis
manganese toxicity
- Risk Factors for Deficiency
- High restricted diets
- Rare genetic abnormalities
- Chronic TPN without manganese
- Risk Factors for Toxicity
- Excess dietary intake
- Occupational exposures
what is this mineral?
manganese
- Severe neurologic abnormalities
- Developmental delays
- Tachycardia
- Tachypnea
- N/V
- Headache
molybdenum deficiency
• Reproductive and fetal
abnormalities
• Uric acid build up
• Decrease BMD
molybdenum toxicity
- Thyroid enlargement (goiter)
- Hypothyroidism
- ↓ T4 and T3
- TSH elevated
- Weight gain
- Fatigue
- Cold intolerance
- Cretinism
iodine deficiency
- Thyroid dysfunction
* Acne-like eruptions
iodine toxicity
- Muscle abnormalities
- Koilonychia
- Pica
- Dry skin
- Anemia
- Fatigue
- Mouth sores
- Impaired cognitive development
- Premature labor
- ↑ perinatal maternal death
iron deficiency
• N/V/D • Cardiomyopathy • Cirrhosis • Diabetes • Arthritis • Increased risk of malignancy (hepatocellular carcinoma)
iron toxicity