CHEMOTHERAPEUTIC MEDS

Question 1

goals of therapy?

Answer 1

selectively kill or suppress cancer cells

minimal or no damage to normal cells

minimize toxicity, adverse events and drug resistance

Question 2

what are the types of chemotherapeutic meds?

Answer 2

alkylating drugs

antimetabolites

Question 3

the alkylating drugs, also known as heavy metal compounds?

Answer 3

carboplatin
cisplatin
oxaliplatin

Question 4

these are antimetabolites with strutural analogues of normal building blocks of DNA stopping production?

AE=myelosuppression

Answer 4

5-fluorouracil
methotrexate
6 mercaptopurine
gemcitibine

Question 5

major adverse drug reactions of chemo?

Answer 5

palmer-palmar erythema
-capecitabine

nail changes

alopecia

Question 6

supportive care for myelosuppression? (like neutropenia prevention)

Answer 6

filgrastim
pegfilgrastim
sargramostim

Question 7

supportive care for anemia?

Answer 7

RBC transfusions

recombinant erythropoietin if hemoglobin <10 g/dl

• epoetin alpha
• darbepoeting alpha

Question 8

supportive care for mucositis?

Answer 8

5-Fu, Doxorubicin, MTX

painful ulcer in mouth