MOA SMOKING CESSATION

Question 1

1st line tx drug used as a dopamine and NE re-uptake inhibitor

Answer 1

bupropion

Question 2

1st line tx drug used for partial neuronal alpha 4 and beta 2 nicotinic receptor agonist and prevents nicotine from stimulating the reward pathway

Answer 2

varenicline

Question 3

2nd line tx drug for central alpha-2 agonist

off label indication-smoking cessation that suppresses W/D effects

Answer 3

clonidine

Question 4

2nd line tx drug thats a tricyclic antidepressant

Answer 4

nortriptyline