MOAs Flashcards

1
Q

suppress acid secretion by inhibiting the parietal cell H/K ATP pump

A

PPI

omeprazole
esomeprazole
pantoprazole
lansoprazole
rabeprazole
dexlansoprazole
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2
Q

competitive inhibition of histamine at H2 (not H1 so its not as effective as a histamine and doesnt cause H1 antagonist sedation)

A

H2 receptor antagonist

cimetidine
famotidine
rantidine
nizatidine

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3
Q

mucosal protective agent

coats ulcers protecting against further damage

treats diarrhea by inhibiting chloride secretions

A

mucosal protective agents

bismuth subsalicylate

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4
Q

mucosal protective agent

prevention of NSAID mucosal injury

A

misoprostol

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5
Q

mucosal protective agent

duodenal ulcer treatment

prevention of mucositis
-may prevent absorption of other drugs

A

sucralfate

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6
Q

weak bases that react w/ HCL to form salt and water

A

antacids

  • calcium carbonate
  • magnesium hydroxide
  • aluminum hydroxide
  • sodium bicarbonate
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