MOAs Flashcards
1
Q
suppress acid secretion by inhibiting the parietal cell H/K ATP pump
A
PPI
omeprazole esomeprazole pantoprazole lansoprazole rabeprazole dexlansoprazole
2
Q
competitive inhibition of histamine at H2 (not H1 so its not as effective as a histamine and doesnt cause H1 antagonist sedation)
A
H2 receptor antagonist
cimetidine
famotidine
rantidine
nizatidine
3
Q
mucosal protective agent
coats ulcers protecting against further damage
treats diarrhea by inhibiting chloride secretions
A
mucosal protective agents
bismuth subsalicylate
4
Q
mucosal protective agent
prevention of NSAID mucosal injury
A
misoprostol
5
Q
mucosal protective agent
duodenal ulcer treatment
prevention of mucositis
-may prevent absorption of other drugs
A
sucralfate
6
Q
weak bases that react w/ HCL to form salt and water
A
antacids
- calcium carbonate
- magnesium hydroxide
- aluminum hydroxide
- sodium bicarbonate