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PHARM II > MOA > Flashcards

MOA Flashcards

1
Q

blocks folic acid leading to DNA synthesis inhibition, typically for its cancer affects

A

methotrexate

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2
Q

inhibits pyrimidine synthesis through inhibition of the mitochondrial enzyme DHODH

A

leflunomide

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3
Q

preferred over MTX and LEF in patients w/ liver disease or those planning to become pregnant who prefer oral tx

A

sulfasalazine

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4
Q 
used for moderate RA
safer for pregnancy
adverse effects can cause retinopathy
triple therapy
-MTX
-sulfasalazine
-hydroxychloroquine
A

hydroxychloroquine

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PHARM II (110 decks)

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