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PHARM II > MODULATION OF CATION CHANNELS > Flashcards

MODULATION OF CATION CHANNELS Flashcards

1
Q

broad spec treating multiple types of seizures

strong CYP3A4

preg cat D leading to cleft lip

status epilepticus
infusion>50 mg/min

AE: gingival hyperplasia, osteomalacia

A

phenytoin

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2
Q

prodrug of phenytoin
indication for status epilepticus
faster than phenytoin

AE: same as phenytoin

A

fosphenytoin

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3
Q

broad spec treating multiple types of seizures

auto inducer

preg cat D

AE: BBW: aplastic anemia, agranulocytosis, SJS

A

carbamazepine

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4
Q

no CYP inhibition or induction

preg cat C

well tolerated and widely used for status epilepticus and Lennox gastaut

AE: rash

A

lamotrigine

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5
Q

absence seizures (patient blanks out for a few seconds), 1st line for it

A

ethosuxamide

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PHARM II (110 decks)

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