IMMUNOSUPPRESSIVE THERAPY Flashcards

1
Q

goals?

A

reduce intensity of immune response

accept donated organ

minimize drug toxicity

prolong graft survival

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2
Q

what are the 3 phases of immunosuppressive therapy?

A

induction
maintenance
rejection

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3
Q

name this phase of immunosuppressive therapy?

high dose/high potency immunosuppressant therapy at time of transplant

  • promote early graft acceptance
  • anti-thymocyteglobulin
  • basiliximab
  • alemtuzumab
A

induction

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4
Q

maintenance drugs for immunosuppressive therapy?

A

corticosteroids
antimetabolites
calcineruin inhibitors
mTOR

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