HIGH YIELD Flashcards
1
Q
tx goals?
A
induce remission
minimize joint pain
slow jt destruction
maximize and maintain quality of life
2
Q
tx for refractory RA?
A
supplementary glucocorticoids
dual or triple DMARD therapy
comb DMARD + TNF inhibitor or non-TNF biologic
3
Q
what is the 1st line for initial therapy?
A
conventional DMARDs, methotrexate
4
Q
what are the conventional DMARDs?
A
methotrexate
leflunomide
hydroxychloroquine
sulfasalazine
5
Q
what are the adverse effects of methotrexate?
prevent AE with?
monitor using?
A
pulmonary toxicity, hepatotoxicity
folate
leucovorin
CBC w/ Dif
renal fx
liver fx
6
Q
MTX precautions?
A
preg
immunizations
alcohol
7
Q
what conventional DMARD is teratogenic?
A
leflunomide
8
Q
this conventional DMARD can cause retinopathy if on it for 5 yrs, so a baseline eye exam is necessary?
A
hydroxychloroquine
