MOA

Question 1

agents can cause nausea and vomiting?

Answer 1

post op nausea and vomiting

Question 2

name the type for PONV:

antagonize serotonin receptor (so no affect on dopamine/ACh)

“-tron”

Answer 2

5-HT3 antagonist

Question 3

name the type for PONV:

inhibits substance P from binding to NK1 receptor

“-pitant”

Answer 3

Neurokinin Receptor Antagonists

Question 4

name this D2 antagonist for PONV:

blocks dopamine in chemoreceptor trigger zone

Answer 4

antipsychotics

Question 5

name this D2 antagonist for PONV:

inhibit both dopamine and muscurinic (ACh) receptors

Answer 5

phenothazines

Question 6

can dexamethasone be used for PONV?

what is it?

Answer 6

yes

glucocorticoid

Question 7

what is the anticholinergic for nausea and vomiting?

put on 2 hrs before PONV, motion sickess, 1st line for N/V related to motion sickness

Answer 7

scopolamine

Question 8

what is this antihistamine for N/V?

not for PONV, for motion sickness

more sedative

Answer 8

diphenhydramine
dimenhydrinate
meclizine
promethazine

Question 9

this is a misc drug used to treat chemo induced N/V, anorexia in patients w/ AIDS

synthetic TCH that is used for patients who do not respond to anything else

Answer 9

dronabinol