T Helper Cells Flashcards

1
Q

TH1 cells produce which cytokines

A

IFN-gamma, GM-CSF, TNF-alpha, IL-3, TNF-B

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2
Q

TH2 cells produce which cytokines

A

IL-4, IL5, IL-10, IL-3, TGF-beta

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3
Q

Th cells

A

CD4+- helper

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4
Q

Tc cells

A

CD8+- cytotoxic

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5
Q

The two helper T cell classes also differ by the type of immune response they produce.

A

While Th1 cells tend to generate responses against intracellular parasites such as bacteria and viruses,

Th2 cells produce immune responses against helminths and other extracellular parasites.

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6
Q

IFN-gamma

A

activates macrophage sand regulates cells

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7
Q

GM-CSF

A

activates macrophages

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8
Q

TNF-alpha

A

activates macrophages

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9
Q

IL-3

A

invoiced in hematopoiesis

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10
Q

TNF-beta

A

involved in inflammatory responses

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11
Q

IL-4

A

activates B cells

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12
Q

IL-5

A

activates b cells

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13
Q

IL-10

A

inhibits macrophages

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14
Q

IL-3

A

involved in hematopoiesis

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15
Q

TGF-B

A

inhibits monocyte activation

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16
Q

TH1/2 are

A

CD4+ T cell subsets