T Helper Cells Flashcards
TH1 cells produce which cytokines
IFN-gamma, GM-CSF, TNF-alpha, IL-3, TNF-B
TH2 cells produce which cytokines
IL-4, IL5, IL-10, IL-3, TGF-beta
Th cells
CD4+- helper
Tc cells
CD8+- cytotoxic
The two helper T cell classes also differ by the type of immune response they produce.
While Th1 cells tend to generate responses against intracellular parasites such as bacteria and viruses,
Th2 cells produce immune responses against helminths and other extracellular parasites.
IFN-gamma
activates macrophage sand regulates cells
GM-CSF
activates macrophages
TNF-alpha
activates macrophages
IL-3
invoiced in hematopoiesis
TNF-beta
involved in inflammatory responses
IL-4
activates B cells
IL-5
activates b cells
IL-10
inhibits macrophages
IL-3
involved in hematopoiesis
TGF-B
inhibits monocyte activation