Opsonisation and Phagocytosis Flashcards
1
Q
after opsonisation with IgA
A
the Fca/mR mediates the uptake of organisms by macrophages and dendritic cells
2
Q
which receptor mediates uptake by neutrophils
A
FcaRI
3
Q
what is common in immunodeficient humans
A
IgA deficiency
4
Q
what can compensate for IgA deficiency
A
IgM- by also binding to plgR- allows transport of Ab across mucosal barriers
5
Q
IgM opsonised organisms are phagocytosed via
A
Fca/mR
6
Q
activating Fc receptor signals through
A
ITAMs
7
Q
polymericIgReceptor is a type of
A
Fc