Immune cells- pictures Flashcards

1
Q

WBCs are

A

much less common than RBC

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2
Q

How many types of WBC (leucocyte)?

A

5

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3
Q

these 5 main types of leucocyte are divided into 2 main classes

A

Granulocytes

Agranulocytes

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4
Q

Granulocytes

A

Basophils, eosinophils, neutrophils

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5
Q

Agranulocytes

A

Lymphocytes and monocytes

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6
Q

all white blood cells are able to move like

A

amoeba, and can migrate out of the blood vessels into the surrounding tissues

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7
Q

what is the commonist type of WBC

A

neutrophils

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8
Q

neutrophils make up

A

60-70% of the total amount of BWC

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9
Q

function of neutrophil

A

Neutrophils are born in the bone marrow. They circulate in the blood for 6-10 hours, and then enter the tissues. They are motile, and phagocytic and will destroy damaged tissue and bacteria. They self destruct after one burst of activity.

They are important in inflammatory reactions.

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10
Q

Sturcutre of neutrophil

A

A single nucleus, which is multilobed

2-5 lobes

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11
Q

How common are eosinophils

A

not common- make up 1-6% of the total white blood cell

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12
Q

function of eosinophils

A

These cells are born in the bone marrow, and migrate from the peripheral blood system after a few hours, into loose connective tissue in the respiratory and gastointestinal tracts. They phagocytose antigen-antibody complexes. They also produce histaminase, and aryl suphatase B, two enzymes that inactivate two inflammatory agents released by mast cells. A high eosinophil blood count may indicate an allergic reaction.

Eosinophils are also important in killing parasitic worms.

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13
Q

structure of eosinophils

A
  • larger than neutrophiils and 3 x the size of RBC
  • 2 lobes to nucleus
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14
Q

basophils are

A

the rarerst tyoe of WBC- make up 1%

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15
Q

function of basophils

A

These cells are involved in immune responses to parasites. They have IgE receptors and the granules are released when the cells bind IgE. These cells also accumulate at sites of infection, and the release of prostaglandins, serotonin and histamine help to increase blood flow to the area of damage, as part of the inflammatory response. The degranulation - release of histamine also plays a role in allergic reactions such as hay fever.

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16
Q

structure of basophil

A
  • contains many granules and bilobed nuclues.
17
Q

Lymphocytes are

A

the second most common WBC (20-50%)

18
Q
A
19
Q

B cells develop and mature

A

in the bone marrow

20
Q

T cells are born in the

A

bone marrow and mature in the tymus

21
Q

B cells develop into

A

plasma cells and make antibodies

22
Q

T cells

A

attack viruses, cancer cells and transplants

23
Q

Structure of Lymphocyte

A
  • small but biigger than RBC
  • lymphocytes can look like monocytes, except the lymphocytes do not have a kidney-bean shaped nucleus
  • smaller than monocytes
  • larger lymphocytes are activated lymphocytes
24
Q

Monocytes are

A

the third most common type of WBC- 2-10% of leucocytes are monocytes

25
Q

function of monocytes

A

Monocytes in the circulation are precursors of tissue macrophages that are actively phagocytic. Monocytes circulate in the blood for 1-3 days, and then migrate into body tissues, where they transform into macrophages. They will phagocytose dead cells and bacteria. Some monocytes can also transform into osteoclasts.

Monocytes are important in the inflammatory response.

26
Q

structure of monocyte

A

Largest type of WBC

  • large eccentrically placed nucleus, which is kidney bean shaped
27
Q
A
28
Q
A