Immune cells- pictures Flashcards
WBCs are
much less common than RBC
How many types of WBC (leucocyte)?
5
these 5 main types of leucocyte are divided into 2 main classes
Granulocytes
Agranulocytes
Granulocytes
Basophils, eosinophils, neutrophils
Agranulocytes
Lymphocytes and monocytes
all white blood cells are able to move like
amoeba, and can migrate out of the blood vessels into the surrounding tissues
what is the commonist type of WBC
neutrophils
neutrophils make up
60-70% of the total amount of BWC
function of neutrophil
Neutrophils are born in the bone marrow. They circulate in the blood for 6-10 hours, and then enter the tissues. They are motile, and phagocytic and will destroy damaged tissue and bacteria. They self destruct after one burst of activity.
They are important in inflammatory reactions.
Sturcutre of neutrophil
A single nucleus, which is multilobed
2-5 lobes
How common are eosinophils
not common- make up 1-6% of the total white blood cell
function of eosinophils
These cells are born in the bone marrow, and migrate from the peripheral blood system after a few hours, into loose connective tissue in the respiratory and gastointestinal tracts. They phagocytose antigen-antibody complexes. They also produce histaminase, and aryl suphatase B, two enzymes that inactivate two inflammatory agents released by mast cells. A high eosinophil blood count may indicate an allergic reaction.
Eosinophils are also important in killing parasitic worms.
structure of eosinophils
- larger than neutrophiils and 3 x the size of RBC
- 2 lobes to nucleus
basophils are
the rarerst tyoe of WBC- make up 1%
function of basophils
These cells are involved in immune responses to parasites. They have IgE receptors and the granules are released when the cells bind IgE. These cells also accumulate at sites of infection, and the release of prostaglandins, serotonin and histamine help to increase blood flow to the area of damage, as part of the inflammatory response. The degranulation - release of histamine also plays a role in allergic reactions such as hay fever.