T cell accesory molecules Flashcards
1
Q
Do T cell accesory molecules vary greatly among individuals?
A
No, they are non polymorphic and invariant.
2
Q
Which is the receptor of CD28 and CTLA-4?
A
CD80 and CD86
3
Q
Which receptor is responsible for co-estimulation?
A
CD28
4
Q
In relation to Co-siganlling molecules…
Which molecule is only expressed on activated T cells?
A
CTLA-4
5
Q
Which has a higher affinity for MHC?
CD28 or CTLA-4?
A
CTLA-4
6
Q
What increases the affinity of the integrins?
A
After TCR or chemokine receptro stimulation.
7
Q
Which selectins are activated upon inflammation and migrate to inflammated tissues?
A
E-selectins and P-selectins.
