Pathogenecity of Bacteria Flashcards
Regarding AB exotoxins…
What is the function of the A and B subunits?
A- Toxic effect
B - Binds to specific target cell
What virulence factor of bacteria causes Botulism and Tetanus?
The AB exotoxin
Inhibits neurotransmitter release and neurotransmission.
What type of bacteria is ‘Clostridium tetani’?
Gram positive, spore forming.
What inhibits the tetanus toxin?
The release of the inhibotory nuerotransmitter glycine.
Constant release of Ach, overestimulation, contractions
Which are the bacteria that usually have more exotoxins?
Gram-negative
Where does the cholera toxin usually binds?
It binds to ganglioside receptors
On the surface of intestinal epithelial cells.
Which bacteria produces leuokocydins?
A pore forming endotoxin.
Staphylococcus aureus
Which bacteria produce hemolysins?
Listeria (Listeriolysin) and Streptoccocus (Streptolysins).
Which bacteria produces enzymes that hydorlyze phospholipids?
Clostridium perfringens
Produces Phospholipase C and destroys red and white blood cells.
What can cause septick shock?
Endotoxins (Gram -) and surface molecules (Gram +)
What molecules have more affinity to Fe and get the Fe from transferrin and lactoferrin?
Siderophores
Molecules produced by bacteria so bacteria can use Fe+3
Where can we found hemophpores?
In Gram negative bacteria
What bacteria causes Streptoccocal pharingytis?
Strep Throat
Streptococcus pyogenes
What causes Rheumatic fever?
Antibodies produced against the M protein after Streptoccocal Pharyngitis.
Example of Obligate Intracellular Pathogens
EXÁMEN
Chlamydia trachomatis
