Cell-mediated effector responses Flashcards
1
Q
Which IL induces T cell proliferation?
A
IL-2
2
Q
How can T cyotoxic cells kill?
A
Through the liberation of perforins and granzyme and the expression of the Fas-ligand.
3
Q
After antigen recognition the affinity of… to ICAM-1 increases
A
LFA-1 (Integrin)
4
Q
Which receptor is in charge of ADCC in NK cells?
A
CD16
5
Q
Which receptor in NK cells send an inhibitory signal?
A
KIR receptors
6
Q
What does NKG2D recognize?
A
NKG2D recognizes proteins (MIC-A,MIC-B) expressed in infected cells (under conditions of stress).
7
Q
What process avoids unnecessary macrophage activation?
A
The binding of CD40 (only expressed in infected cells) with CD40L (expressed in T cells).
8
Q
A
