Mechanism of Immune Evasion Flashcards
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What bacteria produces Protein A (which binds to the Ag)?
Staphylococci aureus
To prevent opsonitzation
What bacteria produces protein M
(which binds to the Ag)?
Streptococci pyogenes
To prevent opsonitzation
Which bacteria destroy C3b?
Streptococcus Pyogenes (causa el impétigo ampolloso) and N. meningiditis
What bacteria produces alpha-toxin?
To kill phagocytes.
Clostridium perfringens
Phospholipase C
What bacteria produce leukocidins and alpha-hemolysin?
Which are pore forming
Staphyloccocus Aureus
Which produce the apoptosis of macrophages?
Shigella and Salmonella
Which bacteria have capsules?
Streptococcus pneumoniae, Klebsiella pneumoniae, Haemophillus Influenzae, Neisseria meningiditis, N. gonorrhoeae,
S. pyogenes, Cryptococcus neoformans (yeast) and Bacillus anthracis.
Pneumonia, gripe, cerebro, transmisión sexua, piojo, Criptón, Antártida.
If bacteria have LPS with long O side chains what do they achieve?
They resist complement lysis.
Which is the variablility of E.coli ?
Number of O, K and H types.
188 O-types (LPS), 80 K-types (Capsule) and 56 H-types (flagella).
Which mycroorganisms are able to make Ag variation?
Borrelia burgardorferi and Trypanosoma brucei
Burro y Bruces
Which bacteria has a capsule made of Hyaluronic Acid?
Streptococcus Pyogenes
La de M protein.
Which bacteria has a capsule made of Sialic Acid?
Neisseria meningiditis
Cerebro
Which bacteria produce IgG proteases?
Staphylococcus Aureus and Streptococcus pyogenes
Justamente los de M and A proteins.
In fungi what molecule can shed another one?
Alpha-(1,3) glucans sheads highly immunogenic Beta- (1,3) glucans
