MHC Flashcards

1
Q

Which MHC has B - Microgobulin?

A

MHCI

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2
Q

Chains that bind to Ag in MHCI and MHCII

A

MHC I : alpha 1 & 2 (with alpha 3 and B microglobulin)
MHC II: alpha 1 and B1 (with alpha 2 and B2)

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3
Q

Which MHC presents shorter peptides, of how much Aa long?

A

MHC I

8-10 Aa

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4
Q

This is a characteristic of:

There are many alleles for each MHC gene

A

Polymorphism

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5
Q

This is a characteristic of:

Different genes encode the same type (functionally similar) of molecules

HLA A.B and C . DP, DQ, DR

A

Polygenic genes

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6
Q

Alleles of MHC class I

A

A, B and C

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7
Q

Alleles of MHC class II

A

DP, DQ, DR

Pablo Quiere Ratas (dos porfavor)

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8
Q

Most polymorphic region of the class I and the class II

A

MHC I: alpha 1
MHC II: B1

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9
Q

What allele is associated to recovery against malaria?

A

B53

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10
Q

What alleles set a predisposition for Celiac disease?

A

DQ2 and DQ8

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11
Q
A
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