MHC Flashcards
Which MHC has B - Microgobulin?
MHCI
Chains that bind to Ag in MHCI and MHCII
MHC I : alpha 1 & 2 (with alpha 3 and B microglobulin)
MHC II: alpha 1 and B1 (with alpha 2 and B2)
Which MHC presents shorter peptides, of how much Aa long?
MHC I
8-10 Aa
This is a characteristic of:
There are many alleles for each MHC gene
Polymorphism
This is a characteristic of:
Different genes encode the same type (functionally similar) of molecules
HLA A.B and C . DP, DQ, DR
Polygenic genes
Alleles of MHC class I
A, B and C
Alleles of MHC class II
DP, DQ, DR
Pablo Quiere Ratas (dos porfavor)
Most polymorphic region of the class I and the class II
MHC I: alpha 1
MHC II: B1
What allele is associated to recovery against malaria?
B53
What alleles set a predisposition for Celiac disease?
DQ2 and DQ8