Summary Of Hormone Production Flashcards
Melatonin
Decreases body temperature, increases drowsiness
Secreted from pineal gland
Where is the pineal gland?
Behind the hypothalamus
Outside of the BBB
Hypothalamic releasing hormone
Produced by hypothalamus
Regulates secretion of anterior pituitary hormones
Oxytocin
Produced by hypothalamus
Regulates milk let down and uterine contractions
ADH
Produced in hypothalamus
Regulates reabsorption of water in kidneys
Growth hormone
Anterior pituitary
Growth, secretion f IGF-1
Prolactin
Produced by anterior pituitary
Develops mammary glands and produces milk
TSH
Produced by anterior pituitary
Secretion of thyroid hormones
ACTH
Produced by anterior pituitary
Secretion of adrenal cortical hormones
FSH
Produced in anterior pituitary
Stimulates development of ovarian follicles/spermatozoa
LH
Produced in anterior pituitary
Luteinising hormone - secretion of sex hormones, formation of corpus luteum
Where are oxytocin and ADH stored?
Posterior pituitary gland
T3 & T4
Produced by thyroid gland
Metabolism, heat, growth, CNS development and maturation
Calcitonin
Produced by thyroid gland
Metabolism of calcium and phosphate
PTH
Produced by parathyroid glands
Regulate calcium and phosphate metabolism
ANP/BNP (atrial/brain natriuretic peptide)
Produced in heart
Regulates sodium excretion in the kidneys
IGF-1
Produced in liver
Growth
Thrombopoetin
Produced in liver Produces thrombocytes (platelets)
Hepcidin
Produced in liver
Regulates iron metabolism
Gastrin
Produced in GI tract
Regulates secretion of HCl in stomach
Secretin
Produced in GI tract
Regulates secretion of HCO3 in pancreas
CCK
Produced in GI tract
Secretion of enzymes in pancreas and contraction of gall bladder
Gastric inhibitory peptide (GIP)
Produced in GI tract
Regulates secretion of HCL in stomach and secretion of insulin
GLP-1 GLP-2
Produced in GI tract
Secretion of insulin
Appetite
Insulin
Metabolism of glucose, fat and protein
Produced in endocrine pancreas
Glucagon
Glycogenolysis and gluconeogenesis
Produced in endocrine pancreas
Aldosterone
Produced in adrenal cortex
Regulates Na/K excretion in kidneys
Cortisol
Produced by adrenal cortex
Metabolism & adaptation to stress
Androgens
Produced in adrenal cortex (and testes)
Contributes to sex steroids, growth & function of reproduction organs
Adrenaline/noradrenaline
Produced in adrenal medulla
Metabolism, cardiac function, adaptation to stres
Vit D3 (1,25 OH2)
Produced by kidneys
Calcium absorption from the intestines
Ertyropoietin
Produced in kidneys
Produces erythrocytes
Renin
ENZYME produced in kidneys
Regulates production of angiotensin 1
Oestrogen/progesterone
Produced in ovaries (and in placenta during pregnancy-grows uterus & foetus)
Growth and function of reproductive hormones
Inhibin
Produced in ovaries
Inhibits FSH secretion
Relaxin
Produced in ovaries
Relaxes cervix and pelvic ligaments
Chorionic gonadotropin
Produced in placenta
Regulates secretion of sex hormones
Leptin
Produced by adipocytes
Decreases appetite
Adiponectin
Produced by adipose tissue
Metabolism and angiogenesis (producing new blood vessels)
Vascular endothelial growth factor
Produced by adipose tissue
Angiogenesis
PTHrP
Produced by most tissues
Regulates calcium metabolism
What is acromegaly?
Chronic excess growth hormone
Which 6 hormones does the anterior pituitary secrete? FLAT PiG
FSH LH ACTH TSH Prolactin GH
What are the solubility of these hormones: peptide/protein hormones, steroids, AA derivatives, FA compounds
Water
Lipid
Water/lipid
Lipid
What are eicosaroids?
Hormones derived by FA compounds. 4 groups: prostaglandins, prostacyclins, thromboxanes, leukotrienes