Substance Use Disorder Pharmacotherapy Flashcards
will have nausea/vomiting if drink alcohol
Disulfiram
Naltrexone
Disulfiram
opioid antagonist
Disulfiram
Naltrexone
Naltrexone
Smoking cessation!
Bupropion
Varenicline
Nicotine Replacement
Bupropion
Varenicline
Weight loss!
Bupropion
Varenicline
Nicotine Replacement
Bupropion
used to treat sexual dysfunction)
Bupropion
Varenicline
Nicotine Replacement
Bupropion
SEIZURES (AVOID in HX of Seizures)
Bupropion
Varenicline
Nicotine Replacement
Bupropion
Partial Nicotine agonist- doesn’t activate the dopamine reward pathway associated with nicotine addiction
Bupropion
Varenicline
Nicotine Replacement
Varenicline
Neuropsychiatric effects
Bupropion
Varenicline
Nicotine Replacement
Varenicline
ADVERSE EFFECTS
Similar to Bupropion- can see Neuropsychiatric effects- vivid dreams, depression, mood changes, thoughts of suicide
Bupropion
Varenicline
Nicotine Replacement
Varenicline
BUT THIS IS TITRATABLE- THIS DRUG COMES IN DOSAGE PACKS THAT TAPER YOU DOWN
Bupropion
Varenicline
Nicotine Replacement
Varenicline
Reduce the cravings of nicotineand reduce the severity of withdrawal manifestations Unintended Outcomes
Bupropion
Varenicline
Nicotine Replacement
Varenicline
Work on tapering these down (gum max 6 months use)
Bupropion
Varenicline
Nicotine Replacement
Nicotine Replacement
Nicotine Lozenges
◦ Nicotine Gum
◦ Nicotine Patch
◦ Nicotine Nasal Spray ◦ Nicotine Inhaler
Bupropion
Varenicline
Nicotine Replacement
Nicotine Replacement
Allow lozenge to dissolve in mouth ◦ avoid any oral products (food/drinks) ? minutes prior or during use ◦ Nicotine Lozenges ◦ Nicotine Gum ◦ Nicotine Patch ◦ Nicotine Nasal Spray ◦ Nicotine Inhaler
◦ Nicotine Lozenges
15
Chew slowly and intermittently ◦ avoid any oral products (food/drinks) ? minutes prior or during use ◦ Nicotine Lozenges ◦ Nicotine Gum ◦ Nicotine Patch ◦ Nicotine Nasal Spray ◦ Nicotine Inhaler
◦ Nicotine Gum
15