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Phamacology Summer > Parkinson' > Flashcards

Parkinson' Flashcards

1
Q

PARKINSONS

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A 
levodopa
carbidopa
entacapone
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
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2
Q

ALZHEIMERS

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

donepezil
memantine
rivastigmine

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3
Q

Restless Legs Syndrome

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

levodopa

carbidopa

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4
Q 
Dopamine Replacement:= 
levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

levodopa

carbidopa

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5
Q

is a precursor to DA

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

levodopa

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6
Q

inhibits the peripheral breakdown of levodopa (before it crosses the BBB)

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

carbidopa

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7
Q

ADVERSE EFFECTS
DYSKINESIAS
Melanoma

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

levodopa

carbidopa

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8
Q

Prevents the breakdown of L-DOPA into inactive metabolites in the periphery

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

entacapone

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9
Q

Orange-yellow discoloration of urine

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

entacapone

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10
Q

Hepatocellular injury and liver failure

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

entacapone

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11
Q

Inhibitor MAO-B

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

selegiline

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12
Q 
INCREASED NOREPENIPHRINE
levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

selegiline

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13
Q

INCREASED SEROTONIN

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

selegiline

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14
Q

Hypertensive crisis in high doses/ Cheese effect

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

selegiline

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15
Q

Serotonin Syndrome Risk

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

selegiline

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16
Q

NEVER GIVE AN MAO

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

selegiline

17
Q

Dopamine Agonists

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

pramiprexole/ropinirole /bromocriptine/apomorphine

18
Q

Acromegaly (pituitary tumors) and hyperprolactinemia

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

/bromocriptine

19
Q

To Induce Vomiting in Animals!

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Apomorphine

20
Q 
P
R
A
B
Is ?
levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Pramipexole
Ropinirole
Apomorphine
Bromocriptine

Probably vomit

21
Q

Postural hypotension

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Pramipexole
Ropinirole
Apomorphine
Bromocriptine

22
Q

Sedation- “sleep attacks” seen with

Pramipexole
Ropinirole
Apomorphine
Bromocriptine

A

pramipexole/ropinirole

23
Q

USED TO TREAT
◦ Dyskinesia’s CAUSED by L-DOPA

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Amantadine

24
Q

has anticholinergic properties, may help stimulate DA release

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Amantadine

25
Q

ADVERSE EFFECTS
◦ Anticholinergic
◦ Livedo Reticularis

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Amantadine

26
Q

ADVERSE EFFECTS
◦ Livedo Reticularis

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Amantadine

27
Q

USED TO TREAT
◦ Parkinson’s-treatstremors
◦ Usually used in younger patients vs older

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Benztropine

28
Q

USED TO TREAT
Pseudoparkinsons/ExtrapyramidalSymptoms(EPS) caused by
antipsychotics

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Benztropine

29
Q

is a patch for Alzheimer’s Disease

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Rivastigmine

30
Q

is a pill forAlzheimer’s Disease

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Donepezil

31
Q

give donepezil at night or morning ,

A

night

32
Q

GI upset- most common
-Heart rarely bradycardia
-Lungs
bronchoconstriction COPD/Asthma

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Rivastigmine + Donepezil

33
Q

Moderate to Severe Alzheimer’s Disease

levodopa
donepezil
carbidopa
memantine
entacapone
rivastigmine
amantadine
selegiline
pramiprexole/ropinirole /bromocriptine/apomorphine
benztropine
A

Memantine

Phamacology Summer (48 decks)

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