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Phamacology Summer > REFRESHER OF THE AUTONOMIC NERVOUS SYSTEM +SYMPATHETIC DIVISION DRUGS > Flashcards

REFRESHER OF THE AUTONOMIC NERVOUS SYSTEM +SYMPATHETIC DIVISION DRUGS Flashcards

1
Q

• Autonomic Division Control Which is true?

a. Common: Opposition (two divisions compete)
b. Rare: Complementary (can work in synergy)
c. Rare: Sometimes only one division controls

A

All

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2
Q

Which Involves E activities – exercise, excitement, emergency, and embarrassment.

Para or Sympathetic

A

Sympathetic

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3
Q

Which is – Heart rate increases, and breathing is rapid and deep

Para or Sympathetic

A

Sympathetic

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4
Q

Which is – The skin is cold and sweaty, and the pupils dilate

Para or Sympathetic

A

Sympathetic

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5
Q

Which is – Mydriasis- “Wide Eyed with Fright”

Para or Sympathetic

A

Sympathetic

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6
Q

Which is • Concerned with keeping energy use low in the body

Para or Sympathetic

A

Para

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7
Q

Involves the D activities – digestion, defecation, and
diuresis

Para or Sympathetic

A

Para

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8
Q

Diuresis means ?

A

Peeling

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9
Q

Which involves Blood pressure, heart rate, and respiratory rates are low

Para or Sympathetic

A

Para

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10
Q

Which involves – Gastrointestinal tract activity is high

Para or Sympathetic

A

Para

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11
Q

Which involves – The skin is warm and the pupils are constricted

Para or Sympathetic

A

Para

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12
Q

Which involves Miosis

Para or Sympathetic

A

Para

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13
Q

Acetylcholine (ACh)

Para or Sympathetic

A

Para

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14
Q

Adrenaline

Para or Sympathetic

A

Sympathetic

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15
Q

Epinephrine

Para or Sympathetic

A

Sympathetic

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16
Q

Cholinergic

Para or Sympathetic

A

Para

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17
Q

Norepinephrine (NE)

Para or Sympathetic

A

Sympathetic

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18
Q

Dopamine (DA)

Para or Sympathetic

A

Sympathetic

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19
Q

Muscarinic (M)

Para or Sympathetic

A

Para

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20
Q 
Alpha 1 (α1)
Alpha 2 (α2)

Para or Sympathetic

A

Sympathetic

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21
Q 
Beta 1 (ß1)
Beta 2 (ß2)
Beta 3 (ß3)

Para or Sympathetic

A

Sympathetic

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22
Q

Found at effectors all throughout the body

Nicotinic Receptors (N) or Muscarinic Receptors (M)

A

Muscarinic Receptors (M)

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23
Q

Blood vessels/pressure in the periphery (arteries)

a1, a2, b1, b2

A

a1

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24
Q

• Blood Vessel/Pressure in Eyes

a1, a2, b1, b2

A

a1

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25
Q

Prostate and bladder

a1, a2, b1, b2

A

a1

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26
Q

• Primarily CNS receptors Brain and Eyes

a1, a2, b1, b2

A

a2

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27
Q

control blood pressure.

a1, a2, b1, b2

A

a1

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28
Q

deals with brain and eyes

a1, a2, b1, b2

A

a2

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29
Q

found on target tissues- Heart,
kidney (juxtaglomerular cells), eye

a1, a2, b1, b2

A

b1

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30
Q

– found on target tissues- Lungs, skeletal muscle,
• Smooth muscle of lungs, arteries of skeletal muscle,
uterine smooth muscle, liver

a1, a2, b1, b2, D1

A

b2

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31
Q

increase heart rate.

a1, a2, b1, b2, D1

A

b1

32
Q

brochidialtion and pneumonia

a1, a2, b1, b2, D1

A

b2

33
Q

blood flow to your Kidneys

a1, a2, b1, b2, D1

A

D1

34
Q

? also interacts with other adrenergic receptors, both? and ?, depending on the dose?

alpha, dopamine, beta

A

dopamine
alpha
beta

35
Q

*Adrenergic agonists do NOT interact with ? receptors

alpha, dopamine, beta

A

dopamine

36
Q

? -> ? -> ?

ß, DA, α

A

DA -> ß -> α

37
Q

Low (?)
• + Moderate ()
• + High ()

alpha-1, dopamine, beta-1)

A

Low (dopamine)
• + Moderate (beta) (beta-1)
• + High (alpha) (alpha-1)

38
Q

? activated by adrenalin or Epinephine

alpha, dopamine, beta

A

alpha, beta

39
Q

? only activated by dopamine.

alpha, dopamine, beta

A

dopamine

40
Q

“Fight-or-Flight

A

Sympathetic

41
Q

Involves E activities – exercise, excitement,
emergency, and embarrassment

Para or Sympathetic

A

Sympathetic

42
Q

blood flow to organs is reduced

Para or Sympathetic

A

Sympathetic

43
Q

flow to muscles is increased

Para or Sympathetic

A

Sympathetic

44
Q

Heart rate increases, and breathing is rapid and
deep

Para or Sympathetic

A

Sympathetic

45
Q

The skin is cold and sweaty, and the pupils dilate

Para or Sympathetic

A

Sympathetic

46
Q

Adrenergic Drugs- are ? to Sympathetic system

agonists or antagonist

A

agonists

47
Q

Vasopressors

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline

48
Q

Anti-Adrenergic/Adrenergic Blocking ANTAGONISTS

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Carvedilol/Propranolol/Labetalol, Metoprolol

49
Q

BETA BLOCKERS

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Carvedilol/Propranolol/Labetalol, Metoprolol

50
Q

Selective Beta 1 Blocker

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Metoprolol

51
Q

Non-Selective Beta Blocker

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Carvedilol/Propranolol/Labetalol

52
Q

USES ?
– Lidocaine w/epinephrine subcutaneously

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline

53
Q

USES ?
Anaphylaxis (The Epipen®!)
is this – IM or IV injection!

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline

54
Q

USES ?
Advanced Cardiac Life Support (ACLS)

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline

55
Q

ACLS
– IV Drip – Used for Shock, hypotension,
bradycardia or asystole

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline

56
Q

? dcreases blood flow- Vassocostriction.
– Lidocaine w/? subcutaneously
? keep the lidocaine in place to numb body area.

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline

57
Q

+Chronotropic (HR) and + Inotropic (CO)

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline,

58
Q

Inotropic (?)

CO or HR

A

CO

59
Q

Chronotropic (?)

CO or HR

A

HR

60
Q

Vasoconstriction

a1, a2, b1, b2

A

a1

61
Q

Bronchodilation

a1, a2, b1, b2

A

b2

62
Q 
Treats
Anaphylaxis
Asthma
Emergencies
Cardiac ArrestAsystole (ACLS)
Shock

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline

63
Q

ADVERSE EFFECTS
Alpha1- increased blood pressure!

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline,

64
Q

ADVERSE EFFECTS
Beta 1- Tachycardia, Angina, Dysrhythmia

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline,

65
Q

IV infusion- risk of infiltration/extravasation- SERIOUS DAMAGE! (Antidote:
Phentolamine)

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline,

66
Q

Antidote:
Phentolamine

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Epinephrine/Adrenaline,

67
Q 
Treats
– MI (Heart attacks)
–Hypertension
–Angina (chest pain)
–Dysrhythmias
–Heart failure
–Migraine prophylaxis
–Thyroid Storm/Thyrotoxicosis
–Eye drops specifically- for glaucoma!

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Metoprolol

68
Q 
– MI
–Hypertension
–Angina
–Dysrhythmias
–Heart failure
–Migraine prophylaxis

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Carvedilol/Propranolol/Labetalol,

Metoprolol

69
Q

–Thyroid Storm/Thyrotoxicosis

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Metoprolol

70
Q

–Eye drops specifically- for glaucoma!

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Metoprolol

71
Q

Means that you have increased IntraOcular Pressure (IOP)

MI (Heart attacks)
–Hypertension
–Angina (chest pain)
–Dysrhythmias
–Heart failure
–Migraine prophylaxis
–Thyroid Storm/Thyrotoxicosis
–Glaucoma!
A

Glaucoma

72
Q

Increases IOP

mydriasis or miosis

A

mydriasis

73
Q

decreases IOP

mydriasis or miosis

A

miosis

74
Q

Eyes (eye-drops)= miosis, lower IOP

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Metoprolol

75
Q 
Adverse Side effects
Bradycardia
Can cause heart failure exacerbation
Sexual dysfunction
Mood- Depression, Insomnia, decreased sexual desire
Hypotension, Dizziness, change positions slowly
May mask S/S of hypoglycemia
Never stop suddenly

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Carvedilol/Propranolol/Labetalol, Metoprolol

76
Q

Doesn’t typically matter with or without food
ASSESS: BP and HR-

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Carvedilol/Propranolol/Labetalol, Metoprolol

77
Q

Local eye drops:
Glaucoma (IOP)

Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol

A

Carvedilol/Propranolol/Labetalo

Phamacology Summer (48 decks)

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