REFRESHER OF THE AUTONOMIC NERVOUS SYSTEM +SYMPATHETIC DIVISION DRUGS Flashcards

1
Q

• Autonomic Division Control Which is true?

a. Common: Opposition (two divisions compete)
b. Rare: Complementary (can work in synergy)
c. Rare: Sometimes only one division controls

A

All

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2
Q

Which Involves E activities – exercise, excitement, emergency, and embarrassment.

Para or Sympathetic

A

Sympathetic

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3
Q

Which is – Heart rate increases, and breathing is rapid and deep

Para or Sympathetic

A

Sympathetic

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4
Q

Which is – The skin is cold and sweaty, and the pupils dilate

Para or Sympathetic

A

Sympathetic

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5
Q

Which is – Mydriasis- “Wide Eyed with Fright”

Para or Sympathetic

A

Sympathetic

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6
Q

Which is • Concerned with keeping energy use low in the body

Para or Sympathetic

A

Para

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7
Q

Involves the D activities – digestion, defecation, and
diuresis

Para or Sympathetic

A

Para

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8
Q

Diuresis means ?

A

Peeling

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9
Q

Which involves Blood pressure, heart rate, and respiratory rates are low

Para or Sympathetic

A

Para

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10
Q

Which involves – Gastrointestinal tract activity is high

Para or Sympathetic

A

Para

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11
Q

Which involves – The skin is warm and the pupils are constricted

Para or Sympathetic

A

Para

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12
Q

Which involves Miosis

Para or Sympathetic

A

Para

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13
Q

Acetylcholine (ACh)

Para or Sympathetic

A

Para

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14
Q

Adrenaline

Para or Sympathetic

A

Sympathetic

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15
Q

Epinephrine

Para or Sympathetic

A

Sympathetic

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16
Q

Cholinergic

Para or Sympathetic

A

Para

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17
Q

Norepinephrine (NE)

Para or Sympathetic

A

Sympathetic

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18
Q

Dopamine (DA)

Para or Sympathetic

A

Sympathetic

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19
Q

Muscarinic (M)

Para or Sympathetic

A

Para

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20
Q
Alpha 1 (α1)
Alpha 2 (α2)

Para or Sympathetic

A

Sympathetic

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21
Q
Beta 1 (ß1)
Beta 2 (ß2)
Beta 3 (ß3) 

Para or Sympathetic

A

Sympathetic

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22
Q

Found at effectors all throughout the body

Nicotinic Receptors (N) or Muscarinic Receptors (M)

A

Muscarinic Receptors (M)

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23
Q

Blood vessels/pressure in the periphery (arteries)

a1, a2, b1, b2

A

a1

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24
Q

• Blood Vessel/Pressure in Eyes

a1, a2, b1, b2

A

a1

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25
Prostate and bladder a1, a2, b1, b2
a1
26
• Primarily CNS receptors Brain and Eyes a1, a2, b1, b2
a2
27
control blood pressure. a1, a2, b1, b2
a1
28
deals with brain and eyes a1, a2, b1, b2
a2
29
found on target tissues- Heart, kidney (juxtaglomerular cells), eye a1, a2, b1, b2
b1
30
– found on target tissues- Lungs, skeletal muscle, • Smooth muscle of lungs, arteries of skeletal muscle, uterine smooth muscle, liver a1, a2, b1, b2, D1
b2
31
increase heart rate. a1, a2, b1, b2, D1
b1
32
brochidialtion and pneumonia a1, a2, b1, b2, D1
b2
33
blood flow to your Kidneys a1, a2, b1, b2, D1
D1
34
? also interacts with other adrenergic receptors, both? and ?, depending on the dose? alpha, dopamine, beta
dopamine alpha beta
35
*Adrenergic agonists do NOT interact with ? receptors alpha, dopamine, beta
dopamine
36
? -> ? -> ? ß, DA, α
DA -> ß -> α
37
Low (?) • + Moderate () • + High () alpha-1, dopamine, beta-1)
Low (dopamine) • + Moderate (beta) (beta-1) • + High (alpha) (alpha-1)
38
? activated by adrenalin or Epinephine alpha, dopamine, beta
alpha, beta
39
? only activated by dopamine. alpha, dopamine, beta
dopamine
40
“Fight-or-Flight
Sympathetic
41
Involves E activities – exercise, excitement, emergency, and embarrassment Para or Sympathetic
Sympathetic
42
blood flow to organs is reduced Para or Sympathetic
Sympathetic
43
flow to muscles is increased Para or Sympathetic
Sympathetic
44
Heart rate increases, and breathing is rapid and deep Para or Sympathetic
Sympathetic
45
The skin is cold and sweaty, and the pupils dilate Para or Sympathetic
Sympathetic
46
Adrenergic Drugs- are ? to Sympathetic system agonists or antagonist
agonists
47
Vasopressors Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline
48
Anti-Adrenergic/Adrenergic Blocking ANTAGONISTS Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Carvedilol/Propranolol/Labetalol, Metoprolol
49
BETA BLOCKERS Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Carvedilol/Propranolol/Labetalol, Metoprolol
50
Selective Beta 1 Blocker Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Metoprolol
51
Non-Selective Beta Blocker Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Carvedilol/Propranolol/Labetalol
52
USES ? – Lidocaine w/epinephrine subcutaneously Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline
53
USES ? Anaphylaxis (The Epipen®!) is this – IM or IV injection! Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline
54
USES ? Advanced Cardiac Life Support (ACLS) Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline
55
ACLS – IV Drip – Used for Shock, hypotension, bradycardia or asystole Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline
56
? dcreases blood flow- Vassocostriction. – Lidocaine w/? subcutaneously ? keep the lidocaine in place to numb body area. Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline
57
+Chronotropic (HR) and + Inotropic (CO) Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline,
58
Inotropic (?) CO or HR
CO
59
Chronotropic (?) CO or HR
HR
60
Vasoconstriction a1, a2, b1, b2
a1
61
Bronchodilation a1, a2, b1, b2
b2
62
``` Treats Anaphylaxis Asthma Emergencies Cardiac ArrestAsystole (ACLS) Shock ``` Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline
63
ADVERSE EFFECTS Alpha1- increased blood pressure! Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline,
64
ADVERSE EFFECTS Beta 1- Tachycardia, Angina, Dysrhythmia Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline,
65
IV infusion- risk of infiltration/extravasation- SERIOUS DAMAGE! (Antidote: Phentolamine) Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline,
66
Antidote: Phentolamine Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Epinephrine/Adrenaline,
67
``` Treats – MI (Heart attacks) –Hypertension –Angina (chest pain) –Dysrhythmias –Heart failure –Migraine prophylaxis –Thyroid Storm/Thyrotoxicosis –Eye drops specifically- for glaucoma! ``` Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Metoprolol
68
``` – MI –Hypertension –Angina –Dysrhythmias –Heart failure –Migraine prophylaxis ``` Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Carvedilol/Propranolol/Labetalol, | Metoprolol
69
–Thyroid Storm/Thyrotoxicosis Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Metoprolol
70
–Eye drops specifically- for glaucoma! Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Metoprolol
71
Means that you have increased IntraOcular Pressure (IOP) ``` MI (Heart attacks) –Hypertension –Angina (chest pain) –Dysrhythmias –Heart failure –Migraine prophylaxis –Thyroid Storm/Thyrotoxicosis –Glaucoma! ```
Glaucoma
72
Increases IOP mydriasis or miosis
mydriasis
73
decreases IOP mydriasis or miosis
miosis
74
Eyes (eye-drops)= miosis, lower IOP Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Metoprolol
75
``` Adverse Side effects Bradycardia Can cause heart failure exacerbation Sexual dysfunction Mood- Depression, Insomnia, decreased sexual desire Hypotension, Dizziness, change positions slowly May mask S/S of hypoglycemia Never stop suddenly ``` Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Carvedilol/Propranolol/Labetalol, Metoprolol
76
Doesn’t typically matter with or without food ASSESS: BP and HR- Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Carvedilol/Propranolol/Labetalol, Metoprolol
77
Local eye drops: Glaucoma (IOP) Epinephrine/Adrenaline, Carvedilol/Propranolol/Labetalol, Metoprolol
Carvedilol/Propranolol/Labetalo