Anemia and Hematopoietic Agents Flashcards by Shaquan Moore

Q

ANEMIA
◦Oral Iron
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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Q

ANEMIA
◦ Parenteral Iron
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

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Q

ANEMIA
◦ B Vitamins
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

c. Folic Acid and Cyanocobalamin

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Q

▪ Iron replenishment for the body when dietary is
insufficient (or excessive loss has occurred)
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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Q

Adverse
liquid iron can STAIN teeth
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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Q

Adverse
black stool normal (not a bleed!)
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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Q

avoid administering with oral antibiotics
(fluoroquinolones and tetracyclines)
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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Q

 Avoid caffeine + dairy

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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Q

Overdose: ANTIDOTE: deferoxamine (Desferal ®)

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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Q

▪leading cause of poisonings in children

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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Q

Give on empty stomach for best absorption

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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Q

BOXED WARNING: anaphylactic reactions during any dose ?

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

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Q

IRON DANGEROUS

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

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Q

Use Z-track technique

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

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Q

▪ Hypotension: Check vitals frequently

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

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Q

BOXED WARNING: risk for anaphylaxis

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

Q

Water-soluble, B-complex vitamin (B9

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

Q

Deficiency resulting in Macrocytic Anemia

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

Q

◦ During pregnancy to prevent neural tube defects

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

Q

Malabsorption syndromes

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

Q

◦ May mask symptoms of pernicious anemia

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

Q

Chronic Alcohol use
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

Q

Used to treat pernicious anemia

c. Folic Acid and Cyanocobalamin

A

Cyanocobalamin

Q

Intranasal: Administer 1 hour before or 1 hour after ingestion of hot foods/liquids.
c. Folic Acid and Cyanocobalamin
d. Epoetin alfa, Darbepoetin
alfa

A

Cyanocobalamin

``` USED TO TREAT- ◦ Anemia in CKD c. Folic Acid and Cyanocobalamin d. Epoetin alfa, Darbepoetin alfa ```

d. Epoetin alfa, Darbepoetin | alfa

``` USED TO TREAT- ◦ Chemotherapy induced Anemia (requires REMS) c. Folic Acid and Cyanocobalamin d. Epoetin alfa, Darbepoetin alfa ```

d. Epoetin alfa, Darbepoetin | alfa

Goal is to increase the Hemoglobin and Hematrocit (H/H) so patient is no longer Anemic c. Folic Acid and Cyanocobalamin d. Epoetin alfa, Darbepoetin alfa

d. Epoetin alfa, Darbepoetin | alfa

◦ Milk Shake Analogy c. Folic Acid and Cyanocobalamin d. Epoetin alfa, Darbepoetin alfa

d. Epoetin alfa, Darbepoetin | alfa

``` CONTRA-INDICATIONS ◦ Drug allergy, uncontrolled hypertension, head and neck cancers, risk of thrombosis c. Folic Acid and Cyanocobalamin d. Epoetin alfa, Darbepoetin alfa ```

d. Epoetin alfa, Darbepoetin | alfa

``` BOXED WARNING CANCER, CHRONIC KIDNEY DISEASE:,CARDIOVASCULAR: c. Folic Acid and Cyanocobalamin d. Epoetin alfa, Darbepoetin alfa ```

d. Epoetin alfa, Darbepoetin | alfa

``` BEFORE ADMINISTRATION: Monitor blood pressure (risk for stroke, MI) Monitor hemoglobin and hematocrit (H/H c. Folic Acid and Cyanocobalamin d. Epoetin alfa, Darbepoetin alfa ```

d. Epoetin alfa, Darbepoetin | alfa

``` ADMINISTRATION Single Use Vial, One time use, don’t use vial for multiple doses Do NOT shake/agitate c. Folic Acid and Cyanocobalamin d. Epoetin alfa, Darbepoetin alfa e. Fil –gra-stim ```

d. Epoetin alfa, Darbepoetin | alfa

``` USED TO TREAT- ◦ Chemotherapy induced Neutropenia d. Epoetin alfa, Darbepoetin alfa e. Fil –gra-stim ```

e. Fil –gra-stim

``` ADVERSE EFFECTS- ◦ Bone pain (25% of patients) ◦ Leukocytosis d. Epoetin alfa, Darbepoetin alfa e. Fil –gra-stim ```

e. Fil –gra-stim

``` BEFORE ADMINISTRATION: Monitor CBC twice weekly (WBC/ANC) HOLD IF WBC >10,000, ANC >1,500 d. Epoetin alfa, Darbepoetin alfa e. Fil –gra-stim ```

e. Fil –gra-stim

e. Fil –gra-stim | Monitor ? twice weekly (?)

CBC | WBC/ANC

e. Fil –gra-stim HOLD IF WBC ?, ANC ?

>10,000 | >1,500