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Phamacology Summer > Anemia and Hematopoietic Agents > Flashcards

Anemia and Hematopoietic Agents Flashcards

1
Q 
ANEMIA
◦Oral Iron
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin
A

a. ferrous sulfate (Feosol®)

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2
Q 
ANEMIA
◦ Parenteral Iron
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin
A

b. iron dextran (INFed®)

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3
Q 
ANEMIA
◦ B Vitamins
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin
A

c. Folic Acid and Cyanocobalamin

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4
Q

▪ Iron replenishment for the body when dietary is
insufficient (or excessive loss has occurred)
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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5
Q 
Adverse
liquid iron can STAIN teeth
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin
A

a. ferrous sulfate (Feosol®)

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6
Q 
Adverse
black stool normal (not a bleed!)
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin
A

a. ferrous sulfate (Feosol®)

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7
Q 
avoid administering with oral antibiotics
(fluoroquinolones and tetracyclines)
a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin
A

a. ferrous sulfate (Feosol®)

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8
Q

 Avoid caffeine + dairy

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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9
Q

Overdose: ANTIDOTE: deferoxamine (Desferal ®)

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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10
Q

▪leading cause of poisonings in children

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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11
Q

Give on empty stomach for best absorption

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

a. ferrous sulfate (Feosol®)

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12
Q

BOXED WARNING: anaphylactic reactions during any dose ?

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

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13
Q

IRON DANGEROUS

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

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14
Q

Use Z-track technique

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

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15
Q

▪ Hypotension: Check vitals frequently

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

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16
Q

BOXED WARNING: risk for anaphylaxis

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

b. iron dextran (INFed®)

17
Q

Water-soluble, B-complex vitamin (B9

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

18
Q

Deficiency resulting in Macrocytic Anemia

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

19
Q

◦ During pregnancy to prevent neural tube defects

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

20
Q

Malabsorption syndromes

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

21
Q

◦ May mask symptoms of pernicious anemia

a. ferrous sulfate (Feosol®)
b. iron dextran (INFed®)
c. Folic Acid and Cyanocobalamin

A

Folic Acid

22
Q
  1. Chronic Alcohol use
    a. ferrous sulfate (Feosol®)
    b. iron dextran (INFed®)
    c. Folic Acid and Cyanocobalamin
A

Folic Acid

23
Q

Used to treat pernicious anemia

c. Folic Acid and Cyanocobalamin

A

Cyanocobalamin

24
Q

Intranasal: Administer 1 hour before or 1 hour after ingestion of hot foods/liquids.
c. Folic Acid and Cyanocobalamin
d. Epoetin alfa, Darbepoetin
alfa

A

Cyanocobalamin

25
Q 
USED TO TREAT-
◦ Anemia in CKD
c. Folic Acid and Cyanocobalamin
d. Epoetin alfa, Darbepoetin
alfa
A

d. Epoetin alfa, Darbepoetin

alfa

26
Q 
USED TO TREAT-
◦ Chemotherapy induced Anemia (requires REMS)
c. Folic Acid and Cyanocobalamin
d. Epoetin alfa, Darbepoetin
alfa
A

d. Epoetin alfa, Darbepoetin

alfa

27
Q

Goal is to increase the Hemoglobin and Hematrocit (H/H) so patient is no longer Anemic
c. Folic Acid and Cyanocobalamin
d. Epoetin alfa, Darbepoetin
alfa

A

d. Epoetin alfa, Darbepoetin

alfa

28
Q

◦ Milk Shake Analogy
c. Folic Acid and Cyanocobalamin
d. Epoetin alfa, Darbepoetin
alfa

A

d. Epoetin alfa, Darbepoetin

alfa

29
Q 
CONTRA-INDICATIONS
◦ Drug allergy, uncontrolled hypertension, head and neck cancers,
risk of thrombosis
c. Folic Acid and Cyanocobalamin
d. Epoetin alfa, Darbepoetin
alfa
A

d. Epoetin alfa, Darbepoetin

alfa

30
Q 
BOXED WARNING
CANCER, CHRONIC KIDNEY DISEASE:,CARDIOVASCULAR: 
c. Folic Acid and Cyanocobalamin
d. Epoetin alfa, Darbepoetin
alfa
A

d. Epoetin alfa, Darbepoetin

alfa

31
Q 
BEFORE ADMINISTRATION:
Monitor blood pressure (risk for stroke, MI)
Monitor hemoglobin and hematocrit (H/H
c. Folic Acid and Cyanocobalamin
d. Epoetin alfa, Darbepoetin
alfa
A

d. Epoetin alfa, Darbepoetin

alfa

32
Q 
ADMINISTRATION
Single Use Vial, One time use, don’t use vial for multiple doses
Do NOT shake/agitate
c. Folic Acid and Cyanocobalamin
d. Epoetin alfa, Darbepoetin
alfa
e. Fil –gra-stim
A

d. Epoetin alfa, Darbepoetin

alfa

33
Q 
USED TO TREAT-
◦ Chemotherapy induced Neutropenia
d. Epoetin alfa, Darbepoetin
alfa
e. Fil –gra-stim
A

e. Fil –gra-stim

34
Q 
ADVERSE EFFECTS-
◦ Bone pain (25% of patients)
◦ Leukocytosis
d. Epoetin alfa, Darbepoetin
alfa
e. Fil –gra-stim
A

e. Fil –gra-stim

35
Q 
BEFORE ADMINISTRATION:
Monitor CBC twice weekly (WBC/ANC)
HOLD IF WBC >10,000, 
ANC >1,500
d. Epoetin alfa, Darbepoetin
alfa
e. Fil –gra-stim
A

e. Fil –gra-stim

36
Q

e. Fil –gra-stim

Monitor ? twice weekly (?)

A

CBC

WBC/ANC

37
Q

e. Fil –gra-stim

HOLD IF WBC ?,
ANC ?

A

> 10,000

>1,500

Phamacology Summer (48 decks)

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