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Phamacology Summer > Anti-Hypertensive Therapy Part 2 > Flashcards

Anti-Hypertensive Therapy Part 2 Flashcards

1
Q

Vasodilators for Hypertensive Emergency/Crisis

a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine

A

Sodium nitroprusside

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2
Q

Vasodilators

a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine

A

hydralazine

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3
Q

Diuretic- Thiazides

a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine

A

Hydrochlorothiazide/HCTZ

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4
Q

Calcium Channel Blockers

a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine

A

nifedipine

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5
Q 
USED TO TREAT
◦ Hypertension (also in pregnant patients)
a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

d. Nifedipine

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6
Q 
USED TO TREAT
◦ Tocolytic (delay premature labor)
a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

d. Nifedipine

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7
Q

“Da High Pressure- DHP’s

a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine

A

d. Nifedipine

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8
Q

◦ Minimal to NO Myocardial tissue (minimal to no effect on HR)

a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine

A

d. Nifedipine

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9
Q 
ADVERSE EFFECTS
◦ Reflex Tachycardia (due to drop in BP)
◦Orthostatic Hypotension
◦ Sexual Dysfunction
◦ peripheral edema, DOSE Dependent (10-15%
◦NO GRAPEFRUIT JUICE!
a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

d. Nifedipine

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10
Q 
ADVERSE EFFECTS
Dangerous in unstable angina/MI
◦ Counteract with a beta blocker!
a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

d. Nifedipine

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11
Q

◦ Avoid Grapefruit juice-

a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine

A

d. Nifedipine

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12
Q 
USED TO TREAT
◦ Hypertension
◦ Heart Failure
◦ Edema
a. Sodium nitroprusside
c. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

c. Hydrochlorothiazide/HCTZ

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13
Q 
MECHANISM
◦ work on the distal convoluted tubule in the kidney,
inhibiting Na, Mg, K, and Cl resorption
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

c. Hydrochlorothiazide/HCTZ

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14
Q 
ADVERSE EFFECTS
◦ hyperGLUC
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

c. Hydrochlorothiazide/HCTZ

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15
Q 
ADVERSE EFFECTS
◦ Photosensitivity/Sulfa Allergy
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

c. Hydrochlorothiazide/HCTZ

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16
Q 
NURSING CONSIDERATIONS
◦ Assess patients for dehydration (weight loss/minimal urine
output) (daily weighing)
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

c. Hydrochlorothiazide/HCTZ

17
Q 
NURSING CONSIDERATIONS
◦ Notify provider if CrCl < 30 ml/min (can’t use!
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

c. Hydrochlorothiazide/HCTZ

18
Q 
NURSING CONSIDERATIONS
Monitor electrolytes
hypokalemia
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

c. Hydrochlorothiazide/HCTZ

19
Q 
Adverse Side Effect
hypokalemia
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

c. Hydrochlorothiazide/HCTZ

20
Q 
Can cause toxicity with Lithium
◦ Avoid NSAIDS-
◦ Are you getting the hint with the kidneys? When in doubt, avoid NSAIDS
and Lithium accumulates 
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

c. Hydrochlorothiazide/HCTZ

21
Q 
◦USED TO TREAT
◦ Hypertensive Urgency/Emergency
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

b. Hydralazine

22
Q 
ADVERSE EFFECTS
◦ Fluid retention (with long term use)
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

b. Hydralazine

23
Q 
ADVERSE EFFECTS
Induced lupus-like syndrome (5-10%)
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

b. Hydralazine

24
Q

Cause SLE (Systemic Lupus Erythematosus)

a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine

A

b. Hydralazine

25
Q 
USED TO TREAT
◦ Hypertensive Emergency- Titratable drip
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

a. Sodium nitroprusside

26
Q 
ADVERSE EFFECTS
◦ severe hypotension
◦ CYANIDE TOXICITY
◦ Delirium
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

a. Sodium nitroprusside

27
Q

◦ Must be protected from light, light can break the drug down

a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine

A

a. Sodium nitroprusside

28
Q 
◦ CYANIDE TOXICITY
dangerous to use in renal failure, long periodof use
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine
A

a. Sodium nitroprusside

29
Q

:Delirium, disorientation, weakness, headache, cardiac
abnormalities, death due to CYANIDE TOXICITY
a. Sodium nitroprusside
b. Hydralazine
c. Hydrochlorothiazide/HCTZ
d. Nifedipine

A

a. Sodium nitroprusside

Phamacology Summer (48 decks)

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