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Phamacology Summer > Infectious Diseases- Antibiotics Part 2.pdf > Flashcards

Infectious Diseases- Antibiotics Part 2.pdf Flashcards

1
Q

Treat MRSA (IV only)

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

f. Vancomycin

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2
Q

Clostridium difficile (C.diff) (PO only)

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

f. Vancomycin

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3
Q

Does handsanitizer kill C. Diff?

Yes or No

A

No

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4
Q

Vancomycin treats

a. Clostridium difficile (C.diff) (IV only)
b. Clostridium difficile (C.diff) (PO only)
c. MRSA (PO only)
d. MRSA (IV only)

A

b. Clostridium difficile (C.diff) (PO only)

d. MRSA (IV only)

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5
Q

Which has Nephrotoxicity

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

f. Vancomycin
b. Aminoglycosides
e. Sulfonamides: Sulfa antibiotics

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6
Q

Which has Ototoxicity

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

f. Vancomycin
d. Macrolides (ACE)
b. Aminoglycosides

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7
Q

Which has Histamine release/flushing syndrome

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

f. Vancomycin

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8
Q

Which has a trough with Nephrotoxicity

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

f. Vancomycin

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9
Q

What is Vancomycin trough ?
When is the trough given?

Vancomycin trough levels (?-?mcg/mL)

A

Vancomycin trough levels (10-20mcg/mL)

30 to hour before admidnistaion.

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10
Q

Monitor SCr/BUN?

a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome

A

Nephrotoxicity

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11
Q

Vestibular damage- dizziness/balance

a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome

A

a. Ototoxicity

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12
Q

Cochlea- hearing, tinnitus (ringing in ears), fullness in ears

a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome

A

a. Ototoxicity

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13
Q

Formerly (and still called) “Red Man Syndrome”

a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome

A

c. Histamine release/flushing syndrome

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14
Q

Mast cell degranulation

a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome

A

c. Histamine release/flushing syndrome

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15
Q

Rash, Itching, Flushing

a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome

A

c. Histamine release/flushing syndrome

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16
Q

Tachycardia, Hypotension

a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome

A

c. Histamine release/flushing syndrome

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17
Q

Rare and potentially reversible

a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome
d. Hepatotoxicity
e. PHOTOSENSITIVITY
g. LFT

A

a. Ototoxicity

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18
Q

Useful for Penicillin Allergies

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

d. Macrolides (ACE)

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19
Q

Which deals with Prokinetic- Gastroparesis

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

Erythromycin-

d. Macrolides (ACE)

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20
Q

Which Macrolides (ACE) deal with Prokinetic- Gastroparesis

Azithromycin, Clarithromycin , Erythromycin,

A

Erythromycin

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21
Q

Which has anti-inflammatory properties

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

d. Macrolides (ACE)

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22
Q

Which has QT prolongation?

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

d. Macrolides (ACE)

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23
Q

Which has heart palpitations, dysrhythmias

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

d. Macrolides (ACE)

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24
Q

Which has Torsades de pointe

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

d. Macrolides (ACE)

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25
Q

CYP3A4 drugs is a

Inducer or Inhibitor

A

Inhibitor

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26
Q

Which has CYP3A4 inhibitor?

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

d. Macrolides (ACE)

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27
Q

Which treats Anthrax and Chlamydia

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

28
Q

Which is very irritating to the G.I. tract- can cause ulceration

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

29
Q

Which you take with full glass of water, avoid bedtime b/c of ulcers?

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

30
Q

Which has Hepatotoxicity with larges doses

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

31
Q

Which is Jaundice, anorexia, malaise, fatigue, nausea

a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome
d. Hepatotoxicity
e. PHOTOSENSITIVITY
g. LFT
h. Hypersensitivity Reactions

A

d. Hepatotoxicity

32
Q

Which is stomach cramp and Dark urine?

a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome
d. Hepatotoxicity
e. PHOTOSENSITIVITY
g. LFT
h. Hypersensitivity Reactions

A

d. Hepatotoxicity

33
Q

Which is PHOTOSENSITIVITY

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

34
Q

Which BINDS TO CALCIUM- TOOTH DISCOLORATION

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

35
Q

Avoid Calcium products-Milk, yogurt, antacids, Iron, aluminum, magnesium, zinc products. MultiVitamins

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

g. Fluoroquinolones

36
Q

DO NOT GIVE TO CHILDREN, PREGNANT PATIENTS

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

37
Q

Can suppress bone growth in developing infants, reversible once stopped

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

38
Q

Do not give to Pregnant Women, Nursing Women

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

39
Q

Aviod in Children < 8 years old

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

c. Tetracyclines

40
Q

Treats Pseudomonas aeruginosa

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

b. Aminoglycosides

41
Q

Which is GTN

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfa antibiotics
g. Fluoroquinolones
f. Vancomycin

A

b. Aminoglycosides

42
Q

Which has Neomycin (Neosprone)

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides:Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

b. Aminoglycosides

43
Q

Do NOT mix with Penicillin (in same syringe or IV site)

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides:Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

b. Aminoglycosides

44
Q

Which deals with UTI

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

e. Sulfonamides:Sulfamethoxazole-Trimethoprim

45
Q

kidney issues due to crystallization

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

e. Sulfonamides: Sulfamethoxazole-Trimethoprim

46
Q

Blood dyscrasias- PANCYTOPENIA

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

e. Sulfonamides: Sulfamethoxazole-Trimethoprim

47
Q

Kernicterus in newborns?

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

e. Sulfonamides: Sulfamethoxazole-Trimethoprim

48
Q 
Which
_ Pregnancy (last 2 months)
 Breastfeeding, Infants
 SULFA ALLERGY-what other drugs???
 Don’t forget this causes kernicterus
a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin
A

e. Sulfonamides: Sulfamethoxazole-Trimethoprim

49
Q 
_Photosensitivity (SUNLIGHT)
 Rash/FEVER
 Stevens-Johnson Syndrome/TEN (rare)
a. Ototoxicity
b. Nephrotoxicity
c. Histamine release/flushing syndrome
d. Hepatotoxicity
e. PHOTOSENSITIVITY
g. LFT
h. Hypersensitivity Reactions
A

h. Hypersensitivity Reactions

50
Q 
Which cause 
Photosensitivity (SUNLIGHT)
 Rash/FEVER
 Stevens-Johnson Syndrome/TEN (rare)
a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin
A

e. Sulfonamides: Sulfamethoxazole-Trimethoprim

g. Fluoroquinolones

51
Q

Potential hyperkalemia drugs

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

e. Sulfonamides: Sulfamethoxazole-Trimethoprim

52
Q

Which deals with renal crystalization and hydration?

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

f. Vancomycin

e. Sulfonamides: Sulfamethoxazole-Trimethoprim

53
Q

Broad Gram +/- coverage, Treats them all?

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

54
Q

Tendon rupture/tendonitis

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

55
Q

Exacerbates Myasthenia Gravis

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

56
Q

Peripheral Neuropathy

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

57
Q

CNS mental health disturbance

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

58
Q

outweigh the benefits for patients

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

59
Q

low blood sugar adverse reactions

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

60
Q

increased risk of ruptures or tears in the aorta blood vessel

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

61
Q

QT prolongation

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

62
Q

Hypoglycemia and hypoglycemia coma

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

63
Q

Increased risk for C.Diff or superinfections

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

64
Q

Chelation-zinc, iron, magnesium, calcium, aluminum

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

65
Q

increased Warfarin levels

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

g. Fluoroquinolones

66
Q

For SYMPTOMS of a UTI

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

a. Phenazopyridine

67
Q

STAINS URINE-reddish/orange color

a. Phenazopyridine
b. Aminoglycosides
c. Tetracyclines
d. Macrolides (ACE)
e. Sulfonamides: Sulfamethoxazole-Trimethoprim
g. Fluoroquinolones
f. Vancomycin

A

a. Phenazopyridine

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