Goat Flashcards

1
Q
Uric acid
Colchicine
Allopurinol
Probenecid
Febuxostat
A

CAP the uric acid
Colchicine
Allopurinol
Probenecid

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2
Q
Which Treat Gout and Uric Acid?
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

All

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3
Q
Which is for acute attack- Gout and Uric Acid
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

IV Corticosteroids

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4
Q
USED TO TREAT: ◦ Chronic Gout
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Allopurinol
febuxostat
Probenecid

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5
Q
MECHANISM OF ACTION:
◦ Inhibit Xanthine oxidase- this is needed to make uric acid. End result- less uric acid
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Allopurinol

febuxostat

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6
Q
HYPERSENSITIVITY REACTION (SJS/TEN) FROM? 
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Allopurinol

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7
Q
Cardiac Risk ? FDA Warning
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

febuxostat

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8
Q
Which is symptoms of  (SJS/TEN)
Skin Rash
Fever
Lips peeling
Mouth sores ◦ Sore throat
Fatigue
None
All
A

All

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9
Q
Fap= ? which is 
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

febuxostat
Allopurinol
Probenecid
Chronic Gout

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10
Q
MECHANISM OF ACTION:
◦ The kidneys eliminate uric acid. ?
increases the elimination of uric acid in the urine.
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Probenecid

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11
Q
ADVERSE EFFECTS:
◦ Alters urine- so kidney stones, kidney injuries
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Probenecid

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12
Q
USED TO TREAT:
◦ Acute Gout (Gout Flare Ups)
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Colchicine

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13
Q
MECHANISM OF ACTION:
◦ Stops microtubules of WBCs, therefore stops WBCs from entering joints and attack gout crystals. If WBCs attack joints, they further increase inflammation
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Colchicine

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14
Q
ADVERSE EFFECTS:
◦ May target microtubules of our own rapidly multiplying cells. Early warning of this is GI symptoms, late warning is systemic organ damage- Death
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Colchicine

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15
Q
Toxic levels- Myelosuppression- (3 lineages)
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Colchicine

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16
Q
Report any GI symptoms (early warning sign of toxicity)
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Colchicine

17
Q
Give with Food if GI upset occurs (mild)
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Colchicine

18
Q
Continue therapy, it can actually worsen gout attacks
when first starting
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Allopurinol

19
Q
Watch out for hypersensitivity reactions (SJS/TEN)
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Allopurinol

20
Q
◦ Stay hydrated
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Allopurinol

21
Q
Stay hydrated to avoid kidney stones + injury 
◦ Also watch out for rash
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Probenecid

22
Q
Educate patients to immediately report severe GI symptoms or myelosuppression, rhabdomyolysis
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Colchicine

23
Q
Patients will be on this daily
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Probenecid

Allopurinol

24
Q
ACUTE gout (gout flare ups)
NSAIDS 
IV Corticosteroids
Colchicine
Allopurinol
Probenecid
febuxostat
None
All
A

Colchicine