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Phamacology Summer > Heart Failure > Flashcards

Heart Failure Flashcards

1
Q

Digoxin

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milrinone

A 
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
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2
Q

◦ Cardiac Glycoside

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

d. Digoxin

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3
Q

Vasodilator

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milrinone

A

a. BiDil® (hydralazine+isosorbide)

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4
Q

ARNI

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milrinone

A

b. Sacubitril + Valsartan

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5
Q

◦ Inodilator

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milrinone

A

c. Milrinone

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6
Q

Heart Failure
• home/stable/chronic/controlled

•Compensated or •Decompensated

A

•Compensated

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7
Q 
Heart Failure (heart failure exacerbation)
• acute/hospitalization/uncontrolled

•Compensated or •Decompensated

A

•Decompensated

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8
Q

? Toxicity = Hypokalema, Hypomagnesemia, Hypercalcemia

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

d. Digoxin

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9
Q 
•What can cause toxicity?
◦ hypokalemia, 
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

d. Digoxin

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10
Q 
◦ ANTIDOTE:
◦ Digibind ®- Digoxin specific Antibody Fab fragment
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

d. Digoxin

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11
Q

Normal range= 0.5 -2 ng/ml

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

Digoxin

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12
Q

Digoxin

Normal range= ? -? ng/ml

A

0.5 -2 ng/ml

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13
Q 
DRUG- DRUG INTERACTIONS- LOTS!
◦ Diuretics that lower potassium
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

d. Digoxin

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14
Q 
DRUG- DRUG INTERACTIONS- LOTS!
◦ Drugs/Foods that can bind up Digoxin and result in lower levels
◦ Bile Acid Sequestrants- Cholestyramine
◦ Sodium Polystyrene Sulfate- Potassium Binder (Kayexalate)
◦ High Fiber foods like Bran
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

d. Digoxin

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15
Q 
DRUG- DRUG INTERACTIONS- LOTS!
•KINETICS:
• Drug is renally eliminated 
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

d. Digoxin

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16
Q

•MED MATH

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

d. Digoxin

17
Q

Nurses should assess potassium levels (3.5 -5 mEq/L)

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

d. Digoxin

18
Q 
USED TO TREAT
◦ Intended for self identified African American patients who have Heart Failure
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

a. BiDil® (hydralazine+isosorbide)

19
Q 
USED TO TREAT
◦ Heart Failure 
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

b. Sacubitril + Valsartan

20
Q

(an Angiotensin II Receptor Blocker (ARB)

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

b. Sacubitril + Valsartan

21
Q

(new drug- Neprilysn Inhibitor)

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

b. Sacubitril + Valsartan

22
Q 
• Drugs that work on the RAAS can cause injury and death to
a developing fetus
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

b. Sacubitril + Valsartan

23
Q

• Orthostatic hypotension (especially with other BP meds like diuretics

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

b. Sacubitril + Valsartan

24
Q

◦ Lithium can accumulate, potential for toxicity

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

b. Sacubitril + Valsartan

25
Q

◦ Avoid potassium supplements (+ Salt substitutes)

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

b. Sacubitril + Valsartan

26
Q 
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
A 
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
27
Q 
USED TO TREAT
◦ Hemodynamic Support
◦Inotropic Support for Heart Failure
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
A

• Dopamine

28
Q 
USED TO TREAT
◦ Severe, acute heart failure (cardiogenic shock)
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
A

• Dobutamine

29
Q 
(Antidote:
Phentolamine)
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
-milrinone
A
  • Dopamine
  • Dobutamine
  • Phenylephrine
  • Isoproterenol
  • Norepinephrine
  • Epinephrine
30
Q 
USED TO TREAT
◦ PDE3- CHF
◦ PDE4- COPD- Theophylline
◦ PDE5- PENIS- Erectile Dysfunction-
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
-milrinone
A

-milrinone

31
Q 
ADVERSE EFFECTS
◦ dysrhythmias (ventricular)
◦ Hypotension
CONTRA-INDICATIONS:
◦ Can’t use if MI or dysrhythmia
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
-milrinone
A

milrinone

32
Q 
USED TO TREAT
Anaphylaxis
Asthma Emergencies
Pulseless Cardiac
Arrest (ACLS)
Shock
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
A

• Epinephrine

33
Q 
USED TO TREAT
Shock
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
A

Norepinephrine

34
Q 
USED TO TREAT
Systemic: Shock/Hypotension
Local/Oral: Nasal Congestion,
Dry eyes, for eye exam
Local: rectal- hemorrhoids
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
A

Phenylephrine

35
Q 
USED TO TREAT
Cardiogenic Shock to
Bradycardia
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
A

• Isoproterenol

Phamacology Summer (48 decks)

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