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Phamacology Summer > Heart Failure > Flashcards

Heart Failure Flashcards

1
Q

Digoxin

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milrinone

A 
VASOPRESSORS/SHOCK
• Dopamine
• Dobutamine
• Phenylephrine
• Isoproterenol
• Norepinephrine
• Epinephrine
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2
Q

◦ Cardiac Glycoside

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

d. Digoxin

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3
Q

Vasodilator

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milrinone

A

a. BiDil® (hydralazine+isosorbide)

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4
Q

ARNI

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milrinone

A

b. Sacubitril + Valsartan

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5
Q

◦ Inodilator

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milrinone

A

c. Milrinone

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6
Q

Heart Failure
• home/stable/chronic/controlled

•Compensated or •Decompensated

A

•Compensated

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7
Q 
Heart Failure (heart failure exacerbation)
• acute/hospitalization/uncontrolled

•Compensated or •Decompensated

A

•Decompensated

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8
Q

? Toxicity = Hypokalema, Hypomagnesemia, Hypercalcemia

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

d. Digoxin

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9
Q 
•What can cause toxicity?
◦ hypokalemia, 
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

d. Digoxin

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10
Q 
◦ ANTIDOTE:
◦ Digibind ®- Digoxin specific Antibody Fab fragment
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

d. Digoxin

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11
Q

Normal range= 0.5 -2 ng/ml

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

Digoxin

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12
Q

Digoxin

Normal range= ? -? ng/ml

A

0.5 -2 ng/ml

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13
Q 
DRUG- DRUG INTERACTIONS- LOTS!
◦ Diuretics that lower potassium
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

d. Digoxin

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14
Q 
DRUG- DRUG INTERACTIONS- LOTS!
◦ Drugs/Foods that can bind up Digoxin and result in lower levels
◦ Bile Acid Sequestrants- Cholestyramine
◦ Sodium Polystyrene Sulfate- Potassium Binder (Kayexalate)
◦ High Fiber foods like Bran
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

d. Digoxin

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15
Q 
DRUG- DRUG INTERACTIONS- LOTS!
•KINETICS:
• Drug is renally eliminated 
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

d. Digoxin

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16
Q

•MED MATH

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

d. Digoxin

17
Q

Nurses should assess potassium levels (3.5 -5 mEq/L)

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

d. Digoxin

18
Q 
USED TO TREAT
◦ Intended for self identified African American patients who have Heart Failure
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

a. BiDil® (hydralazine+isosorbide)

19
Q 
USED TO TREAT
◦ Heart Failure 
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

b. Sacubitril + Valsartan

20
Q

(an Angiotensin II Receptor Blocker (ARB)

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

b. Sacubitril + Valsartan

21
Q

(new drug- Neprilysn Inhibitor)

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

b. Sacubitril + Valsartan

22
Q 
• Drugs that work on the RAAS can cause injury and death to
a developing fetus
a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c.  Milione
d. Digoxin
A

b. Sacubitril + Valsartan

23
Q

• Orthostatic hypotension (especially with other BP meds like diuretics

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

b. Sacubitril + Valsartan

24
Q

◦ Lithium can accumulate, potential for toxicity

a. BiDil® (hydralazine+isosorbide)
b. Sacubitril + Valsartan
c. Milione
d. Digoxin

A

b. Sacubitril + Valsartan

25
◦ Avoid potassium supplements (+ Salt substitutes) a. BiDil® (hydralazine+isosorbide) b. Sacubitril + Valsartan c. Milione d. Digoxin
b. Sacubitril + Valsartan
26
``` VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine ```
``` VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine ```
27
``` USED TO TREAT ◦ Hemodynamic Support ◦Inotropic Support for Heart Failure VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine ```
• Dopamine
28
``` USED TO TREAT ◦ Severe, acute heart failure (cardiogenic shock) VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine ```
• Dobutamine
29
``` (Antidote: Phentolamine) VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine -milrinone ```
* Dopamine * Dobutamine * Phenylephrine * Isoproterenol * Norepinephrine * Epinephrine
30
``` USED TO TREAT ◦ PDE3- CHF ◦ PDE4- COPD- Theophylline ◦ PDE5- PENIS- Erectile Dysfunction- VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine -milrinone ```
-milrinone
31
``` ADVERSE EFFECTS ◦ dysrhythmias (ventricular) ◦ Hypotension CONTRA-INDICATIONS: ◦ Can’t use if MI or dysrhythmia VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine -milrinone ```
milrinone
32
``` USED TO TREAT Anaphylaxis Asthma Emergencies Pulseless Cardiac Arrest (ACLS) Shock VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine ```
• Epinephrine
33
``` USED TO TREAT Shock VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine ```
Norepinephrine
34
``` USED TO TREAT Systemic: Shock/Hypotension Local/Oral: Nasal Congestion, Dry eyes, for eye exam Local: rectal- hemorrhoids VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine ```
Phenylephrine
35
``` USED TO TREAT Cardiogenic Shock to Bradycardia VASOPRESSORS/SHOCK • Dopamine • Dobutamine • Phenylephrine • Isoproterenol • Norepinephrine • Epinephrine ```
• Isoproterenol

Phamacology Summer (48 decks)

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