Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Phamacology Summer > FTBHIV > Flashcards

FTBHIV Flashcards

1
Q

highly toxic!

a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

d. Amphotericin B/ Liposomal Amphotericin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

SHAKE AND BAKE”- INFUSION REACTION

a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

d. Amphotericin B/ Liposomal Amphotericin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

fever, chills, rigors, muscle pain, nausea and headache around 1 to 3 hours
after drug administration
a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

d. Amphotericin B/ Liposomal Amphotericin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hypo-kalemia, Hypo-kidney

a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

d. Amphotericin B/ Liposomal Amphotericin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Bone Marrow Suppression - RBCs(rare)

a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

d. Amphotericin B/ Liposomal Amphotericin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

For superficial infections (creams, oral

suspension) THRUSH!!!!
a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

b. Nystatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Deals with Thrush

a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

b. Nystatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Found as an oral troche

a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

b. Nystatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

CYP450 enzymes

a. Ketoconazole
b. Nystatin
c. Fluconazole/Ketoconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

c. Fluconazole/ Ketoconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Primarily GI related- N/V/D

a. Ketoconazole
b. Nystatin
c. Fluconazole/ Ketoconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

c. Fluconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Hepatotoxicity
• Sex hormone alteration (decreased libido, gynecomastia, menstrual irregularities)
• GI related (N/V/D/C)
a. Ketoconazole
b. Nystatin
c. Fluconazole/ Ketoconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

c. Ketoconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q 
Which should you be cautious of with
Statins
• Anticoagulants/Warfarin
• Phenytoin/Seizure medications
• Transplant medications- (cyclosporine/tacrolimus)
a. Ketoconazole
b. Nystatin
c. Fluconazole/ Ketoconazole
d. Amphotericin B/ Liposomal Amphotericin B
A

c. Fluconazole/ Ketoconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q 
Which should you be cautious of with
Statins
• Anticoagulants/Warfarin
• Phenytoin/Seizure medications
• Transplant medications- (cyclosporine/tacrolimus)
a. Ketoconazole
b. Nystatin
c. Fluconazole/ Ketoconazole
d. Amphotericin B/ Liposomal Amphotericin B
A

c. Fluconazole/ Ketoconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q 
Requires monitoring of LFTs to assess
for hepatotoxicity.
a. Ketoconazole
b. Nystatin
c. Fluconazole/ Ketoconazole
d. Amphotericin B/ Liposomal Amphotericin B
A

c. Ketoconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

No prazoles with ?

a. Ketoconazole
b. Nystatin
c. Fluconazole/ Ketoconazole
d. Amphotericin B/ Liposomal Amphotericin B

A

c. Fluconazole/ Ketoconazole

AZOLES

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Usually has a skin test(PPD) or blood test result indicating TB infection

Latent or Active TB

A

Both

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

4 drugs x 8 weeks

Latent or Active TB

A

Active TB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

1 or 2 drugs (3 to 9 months)

Latent or Active TB

A

Latent TB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

TB =

A

RIPE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q 
RIPE is for ?
Rifampin
Isoniazid
Pyrazinamide
Ethambutol
A

TB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Red/orange discoloration of bodily fluids!
• This means urine, tears, sweat and saliva
• And this can stain contact lenses!
a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

a. Rifampin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Which is a Liver inducer?

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

a. Rifampin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Which has GI upset

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

a. Rifampin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Which has hepatoxicity

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

a. Rifampin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Fatal hepatitis

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

b. Isoniazid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Hyperglycemia

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

b. Isoniazid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q 
• Peripheral Neuropathy
• Isoniazid depletes pyridoxine (B6)
a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol
A

b. Isoniazid

28
Q

Peripheral Neuropathy

• Isoniazid depletes pyridoxine (B?)

A

B6

29
Q 
drug inhibits CYP liver enzymes
Accumulation of seizure meds
• Phenytoin can cause confusion + ataxia
a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol
A

b. Isoniazid

30
Q

phenytoin and carbamazepine are?

A

seizure meds

31
Q

(Gout flare ups + NON Gout joint pain! (Uric Acid)

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

c. Pyrazinamide

32
Q

• Optic Neuritis that is irreversible

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

d. Ethambutol

33
Q

Purines> Uric Acid> Gout /Pain in Joints

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

c. Pyrazinamide

34
Q

Isolated Nerve Problems, CYP Inhibitor, Insulin, Nausea

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

b. Isoniazid

35
Q

Eye/Vision Problems

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

d. Ethambutol

36
Q

Red discoloration, Rapid Metabolizer

a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol

A

a. Rifampin

37
Q

Clostridium difficile (not commonly used anymore)

a. Hydroxychloroquine
b. Metronidazole

A

b. Metronidazole

38
Q

Disulfirim like reaction with EtOH

a. Hydroxychloroquine
b. Metronidazole

A

b. Metronidazole

39
Q

N/V/D
Metallic Taste (10%)
a. Hydroxychloroquine
b. Metronidazole

A

b. Metronidazole

40
Q

Metallic Taste (10%)

a. Hydroxychloroquine
b. Metronidazole

A

b. Metronidazole

41
Q

CNS
Seizures, ataxia, vertigo, Headache (18%)
a. Hydroxychloroquine
b. Metronidazole

A

b. Metronidazole

42
Q

Peripheral Neuropathy

a. Hydroxychloroquine
b. Metronidazole

A

b. Metronidazole

43
Q

Darkens the urine

a. Hydroxychloroquine
b. Metronidazole

A

b. Metronidazole

44
Q

Super/Supra-infection: candida albicans /yeast infection

a. Hydroxychloroquine
b. Metronidazole

A

b. Metronidazole

45
Q

It use to be used to treat • COVID-19

a. Hydroxychloroquine
b. Metronidazole

A

a. Hydroxychloroquine

46
Q

QT prolongation

a. Hydroxychloroquine
b. Metronidazole

A

a. Hydroxychloroquine

47
Q

• Retinal Damage
• Can be irreversible
a. Hydroxychloroquine
b. Metronidazole

A

a. Hydroxychloroquine

48
Q

Plaquenil®, plaque in eyes

a. Hydroxychloroquine
b. Metronidazole

A

a. Hydroxychloroquine

49
Q

• Profound hypoglycemia

a. Hydroxychloroquine
b. Metronidazole

A

a. Hydroxychloroquine

50
Q

Not to be used in G6PD Deficiency

a. Hydroxychloroquine
b. Metronidazole

A

a. Hydroxychloroquine

51
Q

•Herpes Virus (DNA)

a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir

A

b. Acyclovir, Valacyclovir

52
Q

•Influenza Virus (RNA)

a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir

A

a. Oseltamivir

53
Q

•COVID-19 (SARS-CoV2)

a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir

A

c. Remdesivir

54
Q 
• IV Predominantly:
• Phlebitis
• ROTATE IV Site
a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir
A

b. Acyclovir, Valacyclovir

55
Q

• Phlebitis

a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir

A

b. Acyclovir, Valacyclovir

56
Q

Nephrotoxicity

a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir

A

b. Acyclovir, Valacyclovir

57
Q 
Most common- GI – N/V/D
• Headache, Vertigo
• I still tell patients to stay hydrated
a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir
A

b. Acyclovir, Valacyclovir

Oral

58
Q 
Burning, itching at application site
• Wear gloves 
• Wash affected area with soap and water 
a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir
A

b. Acyclovir, Valacyclovir

Topical

59
Q

For best results, take within 12 hours of onset

a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir

A

a. Oseltamivir

60
Q 
USED TO TREAT:
• COVID-19 in HOSPITALIZED adults and pediatrics (this is an IV therapy)
a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir
A

c. Remdesivir

61
Q 
has both • Hepatotoxicity (AST/ALT)
• Nephrotoxicity (SCr,BUN, Crcl)
a. Oseltamivir
b. Acyclovir, Valacyclovir
c. Remdesivir
A

c. Remdesivir-Both renal and LFT

62
Q 
Major Concern is BONE MARROW SUPPRESSION
(pancytopenia!)
a. Enfuvirtide
b. Maraviroc
c. Zidovudine
A

c. Zidovudine

63
Q

• Hepatomegaly/Fatty Liver

a. Enfuvirtide
b. Maraviroc
c. Zidovudine

A

c. Zidovudine

64
Q

• Lactic Acidosis

a. Enfuvirtide
b. Maraviroc
c. Zidovudine

A

c. Zidovudine

65
Q

Prevention of perinatal HIV transmission Mother to neonate

a. Enfuvirtide
b. Maraviroc
c. Zidovudine

A

c. Zidovudine

Phamacology Summer (48 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions