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Bacte LEC > Streptococcus > Flashcards

Streptococcus Flashcards

1
Q

• anti-phagocytic → protects the organism from being phagocytosed

Component of MUCOID COLONIES

A

Hyaluronic acid capsule

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2
Q

• 80 types
• inhibits activation of complement
* Precipitates fibrinogen → clumps platelets and WBC
* Inhibits the migration of WBC
• anti-phagocytic

A

→ M protein

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3
Q

Group-specific cell wall antigen
• Group A sugar:

A

RHAMNOSE-N-ACETYLGLUCOSAMINE

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4
Q

• binds to Fc region of IgG or IgA
* the Fc region is usually reserved for the immune cells
* Leads to no antigen-antibody
complex which usually initiates the complement activity

A

→ IgG & IgA-binding proteins

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5
Q

cleaves C5a component of complement → inhibits neutrophil chemotaxis in vitro
• leads to problems in initiating inflammatory reaction

A

C5a protease

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6
Q

• allows binding to FIBRONECTIN
in pharyngeal epithelium

A

→ F protein

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7
Q

Attached to M protein
• May allow binding to FIBRONECTIN
* Fibronectin is the binding site for our organisms on membranes of host cells or structures

A

Lipoteichoic acid

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8
Q

Fibronolysin that lyses blood clots

A

STREPTOKINASE

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9
Q

Degrades hosts DNA &RNA

A

STREPTODORNASE

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10
Q

Hydrolyze or break down hyaluronic acid which is part of the connective tissue

A

HYALURONIDASE

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11
Q

Associated with the organism’s ability to destroy WBCS

A

DIPHOSPHOPYRIDINE
NUCLEOTIDASE

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12
Q

→ Exotoxin A→ most potent

Acquired through LYSOGENY

Associated with fever and rashes in scarlet fever

Associated with Streptococcal
Toxic Shock Syndrome (TSS)
• more fatal

A

PYROGENIC EXOTOXINS/ ERYTHROGENIC
TOXINS (A,B,C)

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13
Q

Oxygen stable
Surface HEMOLYSIN
• toxic to human cells
→ Antiphagocytic
NOT antigenic

A

STREPTOLYSIN-S

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14
Q

→ Antigenic
• Induce antibody response
Detect serologically
Also produced by group
C and G

Oxygen liable

A

STREPTOLYSIN-O

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15
Q

I.C.E. → skin infections

A

Impetigo
Cellulitis
Erysipelas

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16
Q

→ Begins as fluid-filled blisters that erupt
→ Creating weeping lesions
→ Lesions would release fluid and eventually cross over (mouth, nose, etc.)
→ Common in young children

A

IMPETIGO

17
Q

→ Inflammation/infection
of deep tissues including the skin
→ Common in middle-aged individuals

A

CELLULITIS

18
Q

→ Itchy and feels hot than the
rest of the body
→ NO PUS PRODUCTION
→ There is EXOTOXIN production
→ increased temperature and rashes

A

ERYSIPELAS (SAINT ANTHONY’S FIRE)

19
Q

→ Red swollen tonsils
→ PUS FORMATION
→ Lasts 3-5 days

A

STREPTOCOCCAL PHARYNGITIS

20
Q

Occurs after Streptococcal pharyngitis or other infections

PYROGENIC EXOTOXIN is present
→ fever, rashes, strawberry tongue

Rashes start from the neck, chest, and arms

A

SCARLET FEVER

21
Q

TOXIN MEDIATED

There is hypotension, multiorgan
failure, fever, erythema, swelling, tachycardia, acute respiratory distress, renal impairment, and shock is observed

Milder compared to
staphylococcal TSS

A

STREPTOCOCCAL TOXIC SHOCK SYNDROME

22
Q

cells turn black removed to stop the infection

Acquired through puncture of a structure that contains the
organism (plant thorn, abrasion by bushes)

Does not go deep but it spreads

A

NECROTIZING FASCIITIS

23
Q

→ Cardiac inflammation and scarring
→ Triggered by autoimmune reaction to infection with the GAS group

A

RHEUMATIC HEART DISEASE

24
Q

→ In the acute stage, the condition may consists of PANCARDITIS

→ Entire layers of the heart may be INFECTED or INFLAMMED (Myocardium, endocardium, epicardium)

A

RHEUMATIC HEART DISEASE

25
Q

→ Systemic disease that affects the CONNECTIVE TISSUE
around the ARTERIOLES
→ Occur after an untreated strep throat due to GAS

A

ACUTE RHEUMATIC FEVER

26
Q

Comprises a specific set of
RENAL DISEASES

• Immunologic mechanism →
triggers inflammation and
proliferation of glomerular tissue that can result in damage to the basement membrane

→ Antigen-antibody complex is
involved

A

ACUTE GLOMERULONEPHRITIS

27
Q

Comprises a specific set of
RENAL DISEASES

• Immunologic mechanism →
triggers inflammation and
proliferation of glomerular tissue that can result in damage to the basement membrane

→ Antigen-antibody complex is
involved

A

ACUTE GLOMERULONEPHRITIS

Bacte LEC (29 decks)

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