LEGIONELLA Flashcards
Primary human pathogen of Legionnaires disease (atypical pneumonia)
acquired via aerosolization of bacteria from contaminated cooling towers or other environmental
Legionella pneumophila
First member of the family Legionellaceae
Legionella pneumophila
1, accounts for 95% of Legionnaires’ disease
• 2-10 days incubation
• Begin with nonproductive cough, fever, headache, myalgia
• Followed by bloody or purulent sputum, rales, dyspnea, shaking chills
• May lead to dissemination - extrapulmonary infection
IL. pneumophila serogroup
A widely publicized outbreak of pneumonia in Philadelphia during the American Legion convention in 1976. Delegates, _____of them developed pneumonia, and____ of them died.
221
34
____species identified and
more than____ serogroups
____ species from humans
60
70
25
Other species:
L. micdadei
L. longbeachae (notable for exposure to gardening materials)
L. dumoffii
Legionella
• 3 patterns of disease:_____,_____,_____
•______ - the predominant manifestation of legionellosis, top 4 cause of CAP
• ______mortality rate
sporadic
epidemic outbreaks
nosocomial clusters
Pneumonia
15%-30%
Pontiac Fever (flulike illness) is caused by
L. pneumophila serogroups 1 & 6.
intracellular survival within macrophages, cell to cell spread, secretes proteolytic enzymes
Legionella
Yellow / Blue-White
L. steelei
Blue-White
L. bozemanii
L. dumoffii
L. gormanii
L. lytica
L. parisiensis
L. tusconensis
Blue-White or Yellow-Green
L. anisa
Red
L. rubrilucens
No Color
L. cardiac
L. feeleii
L. lansingensis
L. londiniensis
L. nagasakiensis
Yellow-Green
Legionella birminghamensis
L. cincinnatiensis
L. hackeliae
L. jordanis
L. longbeachae
L. maceachernii
L. micdadei
L. oakridgensis
L. pneumophila
L. sainthelensi
L. wadworthii
