Sodium Bicarbonate

Question 1

Sodium Bicarbonate Classification

Answer 1

Alkalinizing agent/electrolyte

Question 2

Sodium Bicarbonate Mechanism

Answer 2

Alkaline electrolyte that buffers excess H+

H2O + CO2 H2CO3 H+ + HCO3-

Question 3

Sodium Bicarbonate Pharmacokinetics

Answer 3

Onset: Immediate
Peak Effects: <15min
Duration: 1-2 hours
Half Life: n/a

Question 4

Sodium Bicarbonate Indications

Answer 4

• Metabolic acidosis secondary to OD (ASA, TCA)

- Cardiac arrest with known or suspected hyperkalemia (dialysis pt)

Question 5

Sodium Bicarbonate contraindications

Answer 5

Respiratory acidosis

Question 6

Sodium Bicarbonate side effects/adverse reactions

Answer 6

None in emergency setting

Question 7

Sodium Bicarbonate Dose

Answer 7

Adult & Pedi:

1mEq/kg (initial) iv io

Question 8

Sodium Bicarbonate precautions

Answer 8

Causes metabolic alkalosis when administered in large quantities

Question 9

Sodium Bicarbonate Drug Interactions

Answer 9

• Deactivates catecholamines and vasopressors

- Forms PPT with CaCl2 in IV tubing