Etomidate (Amidate) Flashcards
Etomidate Classification
Sedative/Hypnotic
Etomidate Mechanism of Action
Depresses the reticular activatin system of the brain and potentiates GABA -> causes sedation.
Etomidate Pharmocokinetics
Onset: 10-20m
Peak: <1m
Duration: 3-5m
Half Life: 30-70m
Etomidate Indications/Field Use
Induction agent for RSI
Etomidate Contraindications
Hypersensitivity
Etomidate Side Effects/Adverse Reactions
Myoclonic skeletal muscle movement, apnea, hyperventilation, hypoventilation, laryngospasm, HTN, hypotension, tachycardia, bradycardia, N/V
Etomidate Dose
Adult:
0.3mg/kg IV, IO over 15-30s
Pedi:
0.3mg/kg IV, IO over 15-30s
Etomidate Precautions
Consider alternate sedative in patients with severe asthma
Etomidate Drug Interactions
May prolong respiratory depression and apnea with Verapamil