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Drug Cards > Acetaminophen (Tylenol) > Flashcards

Acetaminophen (Tylenol) Flashcards

1
Q

APAP Classification

A

Antipyretic/Analgesic

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2
Q

APAP Mechanism

A

COX inhibitor -> elevation of pain threshold, antipyretic by action on hypothalamic heat regulatory center

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3
Q

APAP Pharmacokinetics

A

Onset: 15-30m
Peak: 30-120m
Duration: 3-4h
Half Life: 1-3h

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4
Q

APAP Indications/Field Use

A

Pediatric fever

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5
Q

APAP Contraindications

A

Hypersensistivity

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6
Q

APAP Side Effects/Adverse Reactions

A

Dizziness, ABD pain, hypoglycemia, N/V

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7
Q

APAP Dose

A

Pedi:

15 mg/kg PO q4-6h PRN, max dose 4g/day

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8
Q

APAP Precautions

A
  • Metabolized by liver - OD can be toxic
  • Does not have anti-platelet aggregation effect
  • Does not have peripheral anti-inflammatory effect
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9
Q

APAP Drug Interactions

A

Chronic excessive use of alcohol increases risk of hepatotoxicity

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