Glucagon (Glucagon Emergency Kit) Flashcards

1
Q

Glucagon Classification

A

Hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Glucagon Mechanism

A

Liver - Glucagon causes activation of glucagon G-proten 2nd messenger cAMP, which leads to a cascade of reactions that allow glucose to be released from glycogen polymers.
Heart - increased cAMP results in calcium entry from ECF and release from sarcoplasmic reticulum -> + chronotropy, inotropy, dromotropy
Lower esophageal sphincter - increased cAMP causes SMC relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Glucagon Pharmacokinetics

A

Onset: 5-20m
Peak: 30m
Duration: 1-2h
Half Life: 5-10m

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Glucagon Indications

A
  • Hypoglycemia, inability to gain IV access
  • Esophageal food bolus impaction
  • Beta-blocker/Ca2+ channel blocker OD/toxicity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Glucagon Contraindications

A
  • Pheochromocytoma

- Hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Glucagon Side Effect/Adverse Reactions

A

HA, dizziness, N/V, hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Glucagon Dose

A

Adult:
Hypoglycemia/Food Bolus: 1mg IM
Ca2+ channel/Beta-blocker OD: 0.1mg/kg IV up to 5mg, repeat in 5m PRN
Pedi:
Hypoglycemia: 0.02mg/kg IM (max dose = 1mg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Glucagon Precautions

A

Only effective in hypoglycemia if sufficient glycogen stores in liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Glucagon Drug Interactions

A

None EMS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly