Nitrous Oxide (Nitronox, Entonox) Flashcards
1
Q
NO Classification
A
Analgesic/Anesthetic Gas
2
Q
NO Mechanism
A
NMDA (Glutamate)-R antagonist -> blockade of neuronal signals to the conscious mind from other parts of the brain, creating dissociative anesthesia, euphoria, and analgesia.
3
Q
NO Pharmacokinetics
A
Onset: 2-5m
Peak: 2-5m
Duration: 2-5m
Half Life: 5m
4
Q
NO Indications/Field Use
A
- Acute musculoskeletal pain
- Pain associated with burns
- Ischemic chest pain
5
Q
NO Contraindications
A
- AMS 2° to drugs, EtOH, or head injury
- Inability to comprehend verbal instructions
- Patient with COPD, ABD pain/distention, or thoracic injury suspicious for pneumothorax
- Facial trauma
6
Q
NO Side Effects/Adverse Reactions
A
Dizziness, light-headedness, AMS, hallucinations, N/V
7
Q
NO Dose
A
Adult:
50/50 mixture of oxygen and NO - self administered until the pt notes relief or drops the mask
8
Q
NO Precautions
A
- Use only in well ventilated area
- May be impossible to administer in temperatures less than 21°F
9
Q
NO Drug Interactions
A
May potentiate other CNS depressants including narcotics, sedatives, hypnotics, and EtOH.
