Olanzapine (Zyprexa) Flashcards
1
Q
Olanzapine Classification
A
Antipsychotic
2
Q
Olanzapine Mechanism
A
SSRI, NE reuptake inhibitor -> antipsychotic and anticholinergic effects
3
Q
Olanzapine Pharmacokinetics
A
Onset: <30m
Peak: 6h
Duration: Varies
Half Life: 21-54h
4
Q
Olanzapine Indications/Field Use
A
- Acute psychosis or agitation
- Alzheimer’s disease
5
Q
Olanzapine Contraindications
A
Hypersensitivity
6
Q
Olanzapine Dose
A
Adult:
10mg IM
Pedi:
Not established
7
Q
Olanzapine Side Effects/Adverse Reactions
A
Myalgia, somnolence, dizziness, tremor, tachycardia, postural hypotension, nausea, dry mouth
8
Q
Olanzapine Precautions
A
- Caution in pt with CV disease, predisposition for hypotension and Parkinson’s disease
- Must be reconstituted in 3mL sterile water prior to administration
9
Q
Olanzapine Drug Interactions
A
Potentiates hypotensive effects of antihypertensives