Second Line of Defence - Introduction Flashcards
1
Q
Is Second Line of Defence specific or non-specific?
A
Non-specific
2
Q
State some characteristics of Second Line of Defense
A
- Rapid - so pathogen has no time to establish
- Present in all animals
- No immunological memory
- Same response
3
Q
What are White Blood Cells?
A
Leukocytes - are cells of immune system that help fight infection/disease
4
Q
What receptors do WBCs have?
A
Toll-like receptors (TLRs)
5
Q
What is purpose of TLRs?
A
Recognise Microbial/pathogenic molecules called Pathogen-Assosciated molecular Patterns (PAMPs)
6
Q
What are charactristics of PAMPs?
A
Common to lots of pathogens allowing leukocytes to identify various pathogens
7
Q
How do TLRs and PAMPs interact?
A
They bind together due to their complementary shape
8
Q
What are antigens?
A
Substances that trigger immune responses
9
Q
State important cells and molecules of Second Line of Defence
5 of them
A
- Phagocytes
- Mast Cells
- Complement proteins
- Cytokines
- Natural Killer Cells
