renal 7 - acid base Flashcards
when is arterial plasma pH acidosis
when its under 7.35
when is arterial plasma pH alkylosis
when its above 7.45
what is the pH for normal ACF
between 7.35 and 7.45
which pH are fatal
under 6.8 above 7.8
what is an acid in terms of H+
releases H+ in solution
what is an base in terms of H+
accepts H+ in solution
what is a volatile acid
CO2
what is a non volatile acid
organic and inorganic acids from other sources than CO2
what does metabolism of sulfur containing amino acids produce
sulfuric acid, a non volatile acid
what does metabolism of lysine, arginine and histidine produce
hydrochloric acid
what is a buffer
any substance that binds to H+
what is a buffer composed of
a weak acid and its conjugate base
what is the buffer in the extracellular system
CO2 HCO3-
what are the intracellular buffers
phosphate ions and proteins
what are the intracellular buffers
hemoglobin
which organs are responsible for balancing [H+]
kidneys and lungs
what does carbonic anhydrase do
turn CO2 +H2O into H2CO3-
what causes the generation of H+ from H2 CO3-
passage of blood through peripheral tissues
do lungs regulate H+ long term or short term
short term
what causes respiratpry inbalances
hyper/oventilation, resp. malfunction
what does high [H+] do to ventilation
stimulates
what does low [H+] do to ventilation
inhibits
do kidneys regulate H+ long term or short term
long term
what do kidneys do to help alkalosis
kidneys excrete more bicarbinate
