Prostaglandin And Eicosanoids Flashcards
COX
1
2
Many tissues normal processes
Inflammatory
Arachidonic acid derivatives
Straight chain leukotriene
Cyclic prostacyclin prostaglandin thromboxane
Prostaglandin E1 analogs
Misoprostol
Alprostadil
PUD
NSAID induced gastritis prevention
Abortifacient
WOF Moebius sequence, miscarriage
Misoprostol
E1
Maintain PDA
Erectile dysfunction
WOF Priapism
Alprostadil
E1
Low conc contract
High conc relax uterine and cervical sm
For labor induction and cervical ripening
Abortifacient
Dinoprostone
Prostaglandin F2a analogs
Carboprost
Latanoprost
Control of postpartum hemorrhage
Abortifacient
Carboprost
F2a
Glaucoma
WOF permanent eye color change
Latanoprost
F2a
Prostaglandin I2 analog
Pulmonary hpn, reduces platelet aggregation in dialysis machines
Epoprostenol