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Antiparasitic Flashcards

0
Q

Blood schizonticide
Prevents polymerization of heme to hemozoin
Nonfalciparum malaria
WOF retinal damage and auditory impairment porphyria

A

Chloroquine

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1
Q

Tissue schizonticide
Gametocide
Eradicates hypnozoites
Radical cure and terminal prophylaxis of vivax and ovale
WOF methemoglobinemia hemolysis in G6PD patients

A

Primaquine

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2
Q 
Blood schizontocide
Complexes DNA to prevent strand separation
Chloroquine resistant malaria
Severe falciparum malaria
DOC PREGNANT MALARIA
WOF HEMOLYSIS IN BLACKWATER FEVER
A

Quinine

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3
Q

Blood schizonticide
Chemoprophylaxis in chloroquine resistant areas
WOF conduction defects and psychosis

A

Mefloquine

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4
Q

Blood schizonticide
Impairs progeny of malarial apicoplast genes
WOF Tooth enamel dysplasia
Do not drink with MILK

A

Doxycycline

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5
Q

Blood schizonticide

Uncomplicated falciparum DOC

A

Artemther lumefantrine

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6
Q

Blood schizonticide
Tissue schizonticide
Tx and prophy of chloroquine resistant falciparum

A

Atovaquone Proguanil

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7
Q

Blood schizontocide and Sporonticide
Chlroquine resistant falciparum
WOF FA deficiency

A

Sulfadoxine Pyrimethamine

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8
Q

Malaria chemoprophylaxis

A

Chloroquine
Mefloquine and Malarone
Doxycycline

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9
Q

Asymptomatic cyst carriers of Entamoeba histolytica DOC

A

Diloxanide Furoate

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10
Q

Backup drug for severe intestinal and extraintestinal amebiasis

A

Emetine

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11
Q

Mild to severe intestinal amebiasis

WOF Thyroid enlargement and neurotoxicity

A

Iodoquinol

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12
Q

DOC severe intestinal and extraintestinal amebiasis

WOF metallic taste

A

Metronidazole

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13
Q

Backup for asymptomatic cyst carriers

A

Paromomycin

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14
Q

DOC CRYPTOSPORIDIOSIS

Metronidazole resistant amebiasis

A

Nitazoxanide

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15
Q

DOC PNEUMOCYSTOSIS

A

Cotrimoxazole

16
Q

Backup for pneumocystosis

A

Pentamidine

17
Q

DOC TOXOPLASMOSIS

A

pyrimethamine and sulfadiazine

18
Q

West African T gambiense
Early
Late

A

Pentamidine

Eflornithine DOC

19
Q

East African T rhodense
Early
Late WOF reactive encephalopathy

A

Suramin

Melarsoprol DOC

20
Q

DOC CHAGAS

A

Nifurtimox

21
Q

DOC LEISHMANIASIS worldwide
WOF sterile abscesses cardiotoxicity
DOC LEISHMANIASIS India

A

Sodium stibogluconate

Amphotericin B

22
Q

DOC ASCARIS ANCYLOSTOMA NECATOR CAPILLARIA

DOC HYDATID DISEASE

A

Albendazole

23
Q

DOC TRICHURIS

A

Mebendazole

24
Q

DOC ENTEROBIUS

A

Pyrantel palmoate

25
Q

DOC FILARIASIS Eye worm diseases

26
Q

DOC Strongyloidiasis

A

Ivermectin

27
Q

DOC Trichinosis

back up for Strongyloidiasis

A

Thiabendazole

28
Q

DOC for trematodes (flukes) and cestodes (flat worms, except Echinococcus)
CI ocular cysticercosis

A

Praziquantel

29
Q

Alternative drug for cestodes (flatworms)

A

Niclosamide

Pharmacology (33 decks)

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