Antidepressants Flashcards
Agitation
Delirium
NM irritability
ECG: prolonged QRS duration, abnormal size and ratio of R and S waves in AVR
TCA overdose
TD 7mg/kg
LD 15mg/kg
- Bicarbonate
Block NE and 5HT transporters
BACKUP FOR MAJOR DEPRESSIVE DISORDERS
Imipramine
TC Antidepressant
Strong NE reuptake inhibitor and weak serotonin reuptake inhibitor. Blocks D2 receptors
WOF akathisia parkinsonism AMENORRHEA GALACTORRHEA SYNDROME SEIZURES
Amoxapine
TC Antidepressant
Blocks presynaptic a2 adrenoreceptors
Blocks serotonin 5HT2 receptors
APPETITE STIMULATION
WOF WEIGHT GAIN marked sedation
Mirtazapine
TC Antidepressant
Inhibits neuronal reuptake of dopamine and NE
SMOKING CESSATION
WOF WEIGHT LOSS PRIAPRISM SEIZURES
Bupoprion
TC Antidepressant
FIRST LINE MDD
WOF erectile dysfunction and withdrawal syndrome
Fluoxetine
SSRI
Erectile Dysfunction
SORE PEniS can't Fuck Hard SSRI Opiates Risperidone Ethanol Propanolol Estrogen Spironolactone Finasteride HCTZ
Fever Agitatiib Tremor Clonus Hyperreflexia Diaphoresis
FAT CHD
Serotonin syndrome
- cyproheptadine
ALTERNATIVE MDD
WOF HPN
Venlafaxine
SNRI
ALTERNATIVE MDD
WOF HEPATOTOXICITY
Duloxetine
SNRI
Block 5 HT2 receptors
WOF PRIAPRISM
Trazodone
Serotonin antagonist
Block 5 HT2 receptors
WOF HEPATOTOXICITY
Nefazodone
Serotonin antagonist
Priaprism
Tigas PeniS Q, AyaW Bumaba Trazodone Papaverine Sildenafik Quetiapine Alprostadil Warfarin Buproprion
Inhibits MAO type B>A
Inc CNS NE and serotonin levels
HPN CRISIS with tyramine in cheese and wine
Phenelzine
MAOI
Fever Acidosis Rhabdomyolysis Trismus Clonis Hpn
Malignant Hyperthermia succinylcholine and halothane Massive ca release Minutes - dantrolene
