Antipsychotic Agents And Lithium Flashcards
Dopaminergic tracts Mentation and mood EPS Prolactin release Eating Copulation
Mesocortical-Mesolimbic Nigostriatal Tuberoinfundibular Medullary-Periventricular Incertohypothalamic
LOW POTENCY
Fewer EPS
More H1 a1 M1 blocks
Chlorpromazine Thioridazine Mesoridazine
VS. HIGH POTENCY
Haloperidol Droperidol Fluphenazine
Fever Encephalopathy Unstable vitals Elevated CPK Rigidity
Neuroleptic Malignant Syndrome
Block D2»5HT2 receptors
Typical antipsychotic
Block 5HT2»D2 receptors
Atypical antipsychotic
WOF EPS failure of ejaculation, corneal and lens deposits, NEUROLEPTIC MALIGNANT SYNDROME, contact dermatitis
Chlorpromazine
Typical antipsychotic
Only antipsychotic with fatal dose
WOF RETINAL DEPOSITS ARRHYTHMIAS
Thioridazine
Typical antipsychotic
Antiemesis
Prochlorperazine
Typical antipsychotic
HUNTINGTON DISEASE
Tourette’s Syndrome
WOF EPS NEUROLEPTIC MALIGNANT SYNDROME
WEAKEST AND LEAST SEDATING
Haloperidol
Typical antipsychotic
REFRACTORY AND SUICIDAL SCHIZOPHRENIA
WOF AGRANULOCYTOSIS SIALORRHEA
only antipsychotic that reduces risk of suicide
Clozapine
Atypical antipsychotic
BIPOLAR DISORDER
ANOREXIA NERVOSA
DEPRESSION
Olanzapine
Atypical antipsychotic
MANIC EPISODES of Bipolar disorder
WOF HYPNAGOGIC HALLUCINATIONS PRIAPRISM
Quetiapine
Atypical antipsychotic
INTRACTABLE HICCUPS
Tourette Syndrome
WOF PROLACTINEMIA
only antipsychotic for schiz in the YOUTH
Risperidone
Atypical antipsychotic
ACUTE MANIA in Bipolar
WOF TORSADES
Inc mortality in elderly pts with dementia
No atropine-like effects, hyperglycemia, hyperprolactinemia or weight gain
Ziprasidone
Atypical antipsychotic
AUTISM COCAINE DEPENDENCE
LEAST SEDATING
No atropine-like effects, hyperglycemia, hyperprolactinemia or weight gain
Aripiprazole
Atypical antipsychotic