Antipsychotic Agents And Lithium Flashcards

0
Q
Dopaminergic tracts
Mentation and mood
EPS
Prolactin release
Eating
Copulation
A
Mesocortical-Mesolimbic
Nigostriatal
Tuberoinfundibular
Medullary-Periventricular
Incertohypothalamic
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1
Q

LOW POTENCY
Fewer EPS
More H1 a1 M1 blocks

A

Chlorpromazine Thioridazine Mesoridazine

VS. HIGH POTENCY
Haloperidol Droperidol Fluphenazine

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2
Q
Fever
Encephalopathy
Unstable vitals
Elevated CPK
Rigidity
A

Neuroleptic Malignant Syndrome

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3
Q

Block D2»5HT2 receptors

A

Typical antipsychotic

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4
Q

Block 5HT2»D2 receptors

A

Atypical antipsychotic

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5
Q

WOF EPS failure of ejaculation, corneal and lens deposits, NEUROLEPTIC MALIGNANT SYNDROME, contact dermatitis

A

Chlorpromazine

Typical antipsychotic

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6
Q

Only antipsychotic with fatal dose

WOF RETINAL DEPOSITS ARRHYTHMIAS

A

Thioridazine

Typical antipsychotic

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7
Q

Antiemesis

A

Prochlorperazine

Typical antipsychotic

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8
Q

HUNTINGTON DISEASE
Tourette’s Syndrome
WOF EPS NEUROLEPTIC MALIGNANT SYNDROME
WEAKEST AND LEAST SEDATING

A

Haloperidol

Typical antipsychotic

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9
Q

REFRACTORY AND SUICIDAL SCHIZOPHRENIA
WOF AGRANULOCYTOSIS SIALORRHEA
only antipsychotic that reduces risk of suicide

A

Clozapine

Atypical antipsychotic

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10
Q

BIPOLAR DISORDER
ANOREXIA NERVOSA
DEPRESSION

A

Olanzapine

Atypical antipsychotic

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11
Q

MANIC EPISODES of Bipolar disorder

WOF HYPNAGOGIC HALLUCINATIONS PRIAPRISM

A

Quetiapine

Atypical antipsychotic

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12
Q

INTRACTABLE HICCUPS
Tourette Syndrome
WOF PROLACTINEMIA
only antipsychotic for schiz in the YOUTH

A

Risperidone

Atypical antipsychotic

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13
Q

ACUTE MANIA in Bipolar
WOF TORSADES
Inc mortality in elderly pts with dementia
No atropine-like effects, hyperglycemia, hyperprolactinemia or weight gain

A

Ziprasidone

Atypical antipsychotic

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14
Q

AUTISM COCAINE DEPENDENCE
LEAST SEDATING
No atropine-like effects, hyperglycemia, hyperprolactinemia or weight gain

A

Aripiprazole

Atypical antipsychotic

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15
Q
DOC MANIC DEPRESSIVE BIPOLAR 
Slow onset of action
WOF EBSTEIN'S ANOMALY
CI sick sinus syndrome
Treat overdose with hemodialysis
A

Lithium

TD 2 meq/L