Alcohols Flashcards
Wernicke
Ataxia
Confusion
Ophthalmegia (EOM paralysis)
Most common neurologic abnormality in chronic alcoholics
Peripheral neuropathy
Korsakoff
Irreversible memory loss
Confabulation
Personality changes
Delirium tremens
Hallucinations
Autonomic instability
Delirium
48-72 h post discontinuation
Alcohol Withdrawal
Electrolytes
Thiamine
Replace alcohol with benzodiazepine
Taper
Treatment of Alcoholism
Naltrexone opioid receptor antagonist
Acamposate NMSA receptor antagonist
Disulfiram inhibits aldehyde dehydrogenase
Inhibit alcohol dehydrogenase
Fomepizole
Main sx of methanol poisoning
Accumulation of formic acid
Visual dysfunction - retinal damage
- ethanol
- fomepizole
Main sx of Ethylene glycol
Accumulation of oxalic acid
Renal damage
- ethanol
- fomepizole