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Pharmacology > Diuretics > Flashcards

Diuretics Flashcards

0
Q

PCT

A

Carbonic anhydrase inhibitor
Acetazolamide

Site of uric acid transport

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1
Q

Drugs that modify salt excretion

A 
Carbonic anhydrase inhibitors
Loop diuretics
Thiazides
K sparing diuretics
Osmotic diuretics
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2
Q

Glaucoma
Mountain sickness

WOF Hep enceph in cirrhotic patients
WOF NAGMA

A

Acetazolamide
Carbonic anhydrase inhibitor
PCT

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3
Q

THICK ASCENDING LH

Na K 2Cl transporter

A

Loop diuretics
Furosemide

Site of Ca and Mg reabsorption

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4
Q

Furosemide

WOF

A 
Ototoxicity
Hypokalemia
Dehydration
Allergy to sulfa
Nephritis
Gout
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5
Q

DCT

NaCl carrier

A

Thiazide diuretics

Ca reabsorption under PTH

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6
Q

Efficacy dec by NSAIDs

A

Furosemide

HCTZ

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7
Q

Thiazide diuretics

WOF

A

HyperGlycemia Lipidemia Uricemia Calcemia

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8
Q

Cortical Collecting Duct

A

K sparing diuretics

  • aldosterone antagonist spironolactone
  • Na blocker amiloride triamterene

Aldosterone
Urine acidification

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9
Q

WOF gynecomastia impotence BPH

WOF hyperchloremic metabolic acidosis

A

Spironolactone

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10
Q

Gynecomastia

A 
Some Drugs Create Awesome Knockers
Spironolactone
Digoxin
Cimetidine
Alcohol
Ketoconazole
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11
Q

Osmotic diuretic
Mannitol
Primarily acts in
Does not act in

A

PCT

Ascending LH

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12
Q

Drugs that modify water excretion

A

Osmotic diuretics
ADH agonist
ADH antagonist

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13
Q

Medullary collecting duct

A

ADH v1 and v2 receptors
Agonist desmopressin
Antagonist connivaptan

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14
Q

Central diabetes insipidus

A

Desmopressin

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15
Q

SIADH

WOF Central pontine myelinosis upon rapid hypoNa correction

A

Conivaptan

16
Q

Urine Na

Urine K

A

Inc

Inc

17
Q

Urine CA

A

Inc in loop

Dec in thiazide

18
Q

Blood pH

A

Acidosis carbonic anhydrase and K sparing

Alkalosis loop and thiazide

Pharmacology (33 decks)

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