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Pharmacology > Hypertension > Flashcards

Hypertension Flashcards

1
Q

Drug classes in hypertension

A 
Diuretics
Sympathoplegics
Vasodilators
Angiotensin antagonists
Renin inhibitor
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2
Q

Diuretics

A

Loop

Thiazide

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3
Q

Inhibit NaCl in distal convoluted tubule
MODERATE diuresis

WOF?

A

Thiazide HCTZ

Hyper Glycemia Lipidemia Uricemia Calcemia
Hypokalemic metabolic alkalosis
Sulfa allergy

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4
Q

Classes of Sympathoplegics

A

CNS Sympathetic Outflow Blockers
Ganglion blockers
Nerve terminal blockers
Adrenoreceptor blockers

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5
Q

CNS sympathetic blockers is also known as

A

A2 agonists
Clonidine
Methyldopa

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6
Q

Ganglion blocker

A

Hexamethonium

Nicotinic AcH receptor blocker

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7
Q

Nerve terminal blockers
Hypertension (obsolete)
SNARE VMAT blocker

WOF?

A

Reserpine

Sedation
Severe depression
SUICIDAL IDEATION

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8
Q

Adrenergic blockers

A

A1 blockers

Beta nonselective blockers

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9
Q

Control BP of pts with pheochromocytoma

A

Phenoxybenzamine nonselective a blocker
Phentolamine nonselective a blocker
Labetalol nonselective b blocker

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10
Q

Vasodilator classes

A

Older oral vasodilators
Ca channel blockers
Parenteral vasodilators

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11
Q

Older oral vasodilators

A

Hydralazine

Minoxidil

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12
Q

Alters intracellular Ca
Relaxes arteriolar smooth muscle
Dec afterload

Pre eclampsia
Hypertension
Heart failure (+ ISDN for BLACKS)

A

Hydralazine

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13
Q

Drug induced lupus

A

Hydralazine
Isoniazid
Procainamide
Penicillamine

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14
Q

Opens K channels in vascular smooth muscle
ALOPECIA
WOF HYPERTRICHOSIS

A

Minoxidil

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15
Q

Calcium blockers

L type channels

A

Non DHP verapamil CARDIAC

DHP nifedipine amlodipine VASCULAR

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16
Q

SVT

A

Esmolol

NDHP Ca blockers

17
Q

WOF gingival hyperplasia, AV block, HF, sinus node depression

A

Verapamil

Non DHP

18
Q

WOF pretibial edema, constipation, nausea, flushing, dizziness

A

Nifedipine

19
Q

Parenteral vasodilators for HYPERTENSIVE EMERGENCY

A

Nitroprusside

Fenoldopam

20
Q

WOF cyanide toxicity

A

Nitroprusside

21
Q

Dopamine agonist

WOF hypokalemia

A

Fenoldopam

22
Q

Angiotensin antagonists

A

ACE-i

ARBs

23
Q

Benefits of angiotensin antagonists

A

Slows ventricular remodeling and survival in heart failure

Delays progression to diabetic retinopathy

24
Q

post MI

A

ACE-I

25
Q

Renin antagonist

A

Aliskiren

26
Q

Malignant Hpn

A

Parenteral vasodilators + loop diuretics and B blockers

27
Q

Inhibit NaK2Cl transporter in thick ascending limp of LH
POWERFUL DIURESIS

Pulmonary edema in acute HF
Hypercalcemia and anion overdose

WOF?

A

Loop Furosemide
Ototoxicity dehydration sulfa allergy
Hypokalemic metabolic alkalosis
Sulfa allergy

Pharmacology (33 decks)

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